摘要
目的 研究结直肠腺癌CT纹理分析征象与其病理组织学的关系。方法 选取本院2018年4月至2019年2月收治85例结直肠癌患者作为研究对象。获取CT参数值,分析结直肠腺癌CT纹理分析征象与其病理组织学的关系。结果 85例结直肠癌均为腺癌,肿瘤直径:1.97~7.02cm,平均3.87cm。低分化24,中分化32例,高分化29例;浸润深度:肌层以上49例,限于肌层36例;其中41例可见淋巴结转移。有淋巴结转移、浸润深度限于肌层高分化者,标准差、熵、不均匀度参数值均明显高于无淋巴结转移转移、浸润深度在肌层以上的低、中分化者(P<0.05);平均值、峰值、偏度与其病理组织学无关(P>0.05)。结论 结直肠腺癌CT纹理分析征象与其病理组织学特征关系密切,其中标准差、熵、不均匀度可有效评估结直肠腺癌生物学特性,具有较高的临床应用价值。
Objective To study the relationship between signs of CT texture analysis of colorectal adenocarcinoma and histopathology. Methods 85 patients with colorectal cancer admitted to our hospital from April 2018 to February 2019 were selected as the research subjects. The CT parameter values were obtained, and the relationship between CT texture analysis signs and histopathology of colorectal adenocarcinoma was analyzed. Results 85 cases with colorectal cancer were all adenocarcinoma. The diameter of the tumor was 1.97-7.02cm, and the average diameter was 3.87cm. 24 cases were poorly differentiated, 32 cases were moderately differentiated, and 29 cases were well differentiated. The infiltration depth of 49 cases was above the muscular layer, and the infiltration depth of 36 cases was limited to the muscular layer;among them, 41 cases showed lymph node metastasis. The standard deviation, entropy, and unevenness parameter values of those with lymph node metastasis, infiltration depth limited to the muscular layer and high differentiation were significantly higher than those with no lymph node metastasis, low and moderate differentiation and infiltration depth above the muscular layer(P<0.05). The average value, peak value and skewness had nothing to do with histopathology(P>0.05). Conclusion The CT texture analysis signs of colorectal adenocarcinoma are closely related to histopathological features. Among them, standard deviation, entropy, and unevenness can effectively evaluate the biological characteristics of colorectal adenocarcinoma and have higher clinical application value.
作者
张二宁
朱鸷翔
鲍志国
张进
ZHANG Er-ning;ZHU Zhi-xiang;BAO Zhi-guo;ZHANG Jin(Ct Room,the First Affiliated Hospital of Henan University,Kaifeng 475001,Henan Province,China)
出处
《中国CT和MRI杂志》
2022年第5期157-159,共3页
Chinese Journal of CT and MRI
基金
河南省医学科技攻关计划联合共建项目(LHGJ20190515)。
关键词
结直肠腺癌
CT纹理分析征象
病理组织学
Colorectal Adenocarcinoma
CT Texture Analysis Signs
Histopathology
