摘要
目的分析止咳散加减治疗老年肺炎的临床效果。方法96例老年肺炎患者,按照患者入院顺序随机分为试验组和对照组,每组48例。对照组患者接受西药抗生素治疗,试验组患者在抗生素治疗基础上给予止咳散加减治疗。比较两组患者相关临床指标、治疗效果、炎症反应指标、不良反应发生情况。结果试验组患者退热时间(1.66±0.52)d、止咳时间(2.61±0.64)d、祛痰时间(4.04±1.05)d、住院时间(5.82±1.23)d均短于对照组的(4.16±0.89)、(3.72±0.78)、(5.81±1.36)、(12.05±2.67)d,差异有统计学意义(t=16.803、7.622、7.137、14.683,P<0.05)。试验组患者治疗总有效率95.83%(46/48)高于对照组的79.17%(38/48),差异具有统计学意义(χ^(2)=6.095,P<0.05)。治疗后,试验组患者C反应蛋白(CRP)水平(6.10±1.87)mg/L低于对照组的(9.58±2.26)mg/L,差异具有统计学意义(t=8.219,P<0.05)。两组不良反应发生率比较,差异无统计学意义(χ^(2)=1.011,P>0.05)。结论老年肺炎治疗中应用中药止咳散加减可以显著提高患者治疗效果,且用药安全可靠,不良反应发生率低,具有临床推广价值。
Objective To analyze the clinical effect of modified Zhike Powder in the treatment of senile pneumonia.Methods A total of 96 cases of senile pneumonia were randomly divided into experimental group and control group according to the order of admission,with 48 cases in each group.Patients in the control group were treated with western medicine antibiotics,and patients in the experimental group were treated with modified Zhike Powder on the basis of antibiotic treatment.The related clinical indicators,therapeutic effects,inflammatory response indicators,and occurrence of adverse reactions were compared between the two groups.Results The antipyretic time(1.66±0.52)d,cough relieving time(2.61±0.64)d,expectorant time(4.04±1.05)d,and hospitalization time(5.82±1.23)d in the experimental group were shorter than(4.16±0.89),(3.72±0.78),(5.81±1.36),and(12.05±2.67)d in the control group,and the differences were statistically significant(t=16.803,7.622,7.137,14.683;P<0.05).The total effective rate 95.83%(46/48)in the experimental group was higher than 79.17%(38/48)in the control group,and the difference was statistically significant(χ^(2)=6.095,P<0.05).After treatment,the C-reactive protein(CRP)level(6.10±1.87)mg/L in the experimental group was lower than(9.58±2.26)mg/L in the control group,and the difference was statistically significant(t=8.219,P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(χ^(2)=1.011,P>0.05).Conclusion The application of traditional Chinese medicine Zhike Powder in the treatment of senile pneumonia can improve the therapeutic effect,and the drug is safe with low adverse reactions,which has the value of clinical promotion.
作者
刘立弘
LIU Li-hong(Occupational Disease Department,Ansteel Group General Hospital Occupational Disease Prevention and Treatment Institute,Anshan 114000,China)
出处
《中国现代药物应用》
2022年第5期177-179,共3页
Chinese Journal of Modern Drug Application
关键词
止咳散加减
老年肺炎
临床效果
不良反应
Modified Zhike Powder
Senile pneumonia
Clinical effect
Adverse reactions
