摘要
目的探讨中西医结合内科治疗重症急性胰腺炎患者的临床效果。方法选取2019年10月至2021年10月盘锦市人民医院收治的88例重症急性胰腺炎患者作为研究对象,按随机数字表法分为常规组与观察组,各44例。常规组给予常规内科治疗,观察组在常规组基础上加用通胰汤治疗,比较两组治疗有效率、血清炎症介质指标、实验室指标。结果观察组治疗有效率高于常规组,差异有统计学意义(P<0.05);观察组患者治疗后肿瘤坏死因子-α(TNF-α)、白细胞介素-8(IL-8)、白细胞介素-10(IL-10)低于常规组,差异有统计学意义(P<0.05);观察组患者治疗后乳酸脱氢酶(LDH)高于常规组,C反应蛋白(CRP)、白细胞计数(WBC)、血淀粉酶(S-Amy)低于常规组,差异有统计学意义(P<0.05)。结论重症急性胰腺炎实施中西医结合内科治疗能够取得理想临床疗效,有助于改善患者LDH、CRP、WBC、S-Amy等指标,减轻炎症反应。
Objective To study the clinical effect of integrated traditional Chinese and Western medicine in the treatment of severe acute pancreatitis. Methods A total of 88 patients with severe acute pancreatitis admitted to Panjin City People’s Hospital were selected as observation objects, and the selected time was from October 2019 to October 2021. According to the random number table,they were divided into routine group and observation group, each with 44 cases. In the analysis group, routine internal medicine treatment and routine internal medicine + integrated traditional Chinese and Western medicine treatment were carried out in clinical practice, and the total effective rate of treatment, serum inflammatory mediator indicators, and laboratory indicators were compared between the groups. Results The statistical study showed that the total effective rate of treatment of severe acute pancreatitis in the analysis group was higher than that in the conventional group, the difference is statistically significant(P<0.05). After treatment, the indexes of TNF-α, IL-8, IL-10, CRP, WBC, and S-Amy in the analysis group were all Lower than the conventional group, the difference is statistically significant(P<0.05). Lactate dehydrogenase(LDH) of the observation group was higher than that of the conventional group, C-reactive protein(CRP), white blood cell count(WBC), and blood amylase(S-Amy) were lower than those of the conventional group after treatment, and the difference was statistically significant(P<0.05). Conclusion The implementation of severe acute pancreatitis with integrated traditional Chinese and western medicine and internal medicine can achieve ideal clinical efficacy, which can help improve patient LDH, CRP, WBC, S-Amy and other indicators and reduce inflammatory response.
作者
张丹
闫伟
ZHANG Dan;YAN Wei(Endoscopic Diagnosis And Treatment Center,Panjin City People's Hospital,Panjin 124221,China)
出处
《中国药物经济学》
2022年第2期118-121,共4页
China Journal of Pharmaceutical Economics
关键词
重症急性胰腺炎
中西医结合
内科
疗效
炎症介质
血淀粉酶
Severe acute pancreatitis
Integrated traditional Chinese and Western medicine
Internal medicine
Curative effect
Inflammatory mediators
Laboratory indicators
