摘要
幽门螺杆菌(Helicobacter pylori,Hp)感染与消化道疾病及全身多个系统的发病相关,其感染率高、致病力强,威胁着人们的身体健康。近年来由于抗生素的滥用,抗生素耐药呈逐年上升趋势,从而导致Hp根除率下降,成为临床棘手的问题。近年来,为了努力提高Hp根除率,国内外学者做了积极探索,提出了“个体化”精准根除治疗的概念,根据患者自身具体情况,选择个体化药物根治方案。本文将对Hp根治联合用药的患者个体化差异作一综述,旨在为临床医师根治Hp选择最佳治疗方案提供具有参考价值的建议。
Helicobacter pylori(Hp)infection is associated with digestive tract diseases and the incidence of multiple systems throughout the body,with a high infection rate and strong pathogenicity,and is threatening people's health.In recent years,due to the abuse of antibiotics,antibiotic resistance has been increasing year by year,which leads to the decline of Hp eradication rate,and it has become a difficult clinical problem.In recent years,in order to improve the Hp eradication rate,domestic and foreign scholars have made active exploration,proposed the concept of"individualized"precise eradication therapy,and selected individualized drug radical cure plan according to the patients'specific circumstances.This article reviews the individualized differences in patients treated with Hp eradication combination,so as to provide valuable suggestions for clinicians to select the best treatment for Hp eradication.
作者
姜鑫
高雪峰
佘强
丁岩冰
Jiang Xin;Gao Xuefeng;She Qiang;Ding Yanbing(School of Medicine,Yangzhou University,Yangzhou 225001,China;Department of Digestive Diseases,Affiliated Hospital of Yangzhou University,Yangzhou 225001,China)
出处
《国际医药卫生导报》
2022年第1期32-37,共6页
International Medicine and Health Guidance News
基金
江苏省社会发展面上项目(BE2019698)
扬州市“十三五”科教强卫专项(YXZX20184)
扬州市重大公共卫生专项。
关键词
幽门螺杆菌
根除治疗
个体化
抑酸剂
抗生素
铋剂
Helicobacter pylori
Eradication therapy
Individualization
Antacid
Antibiotics
Bismuth
