摘要
目的探讨幽门螺杆菌感染与反流性食管炎的相关性。方法选取2011年1月至2014年1月上海市同仁医院收治的600例反流性食管炎患者,根据反流性食管炎洛杉矶分类标准将患者分为A级(417例)、B级(149例)、C级(28例)、D级(4例)、Barrett食管(2例)5级。比较不同分级反流性食管炎患者幽门螺杆菌的感染率及感染程度。结果 600例反流性食管炎患者中,幽门螺杆菌感染241例(40.2%),其中A级幽门螺杆菌感染率为42.0%(175/417)、B级37.6%(56/149)、C级28.0%(8/28)、D级为1/4、Barrett食管1/2;不同分级反流性食管炎患者幽门螺杆菌感染程度比较差异有统计学意义(P<0.05);Spearman相关分析显示,反流性食管炎分级与幽门螺杆菌感染程度呈负相关(r=-0.766,P<0.05)。结论幽门螺杆菌感染与反流性食管炎的发生、发展具有密切相关性,治疗时应予以考虑。
Objective To study the relationship between Helicobacter pylofi infection and reflux esophagitis. Methods Total of 600 patients with reflux esophagitis in Shanghai Tongren hospital from Jan. 2011 to Jan. 2014 were divided into class A （417 cases）,class B （149 cases）, class C （28 cases）, class D （4 cases） and Barrett class 5 （2 cases） according to Los Angeles classification standard of reflux esophagi- tis. The infection rate and infection degree of patients with different degrees of reflux esophagitis were com- pared. Results There were 241 cases （40.2%） of infection with Helicobacter pylori among the 600 patients,among them the infection rate of class A was 42.0% （175/417） ,of class B was 37.6% （56/ 149） , of class C was 28.0% （8/28） , of class D was 1/4, of Barrett was 1/2. There were statistical differ- ences in Helicobacter pylori infection degrees between patients with different classes of reflux esophagitis （ P 〈 0. 05 ）. The Spearman correlation test showed that the levels of reflux esophagitis were negatively correlated with the infection degree of Helicobacter pylofi （ r = - 0. 766,P 〈 0. 05 ）. Conclusion The infection of Helicobacter pylori is closely associated with the occurrence and development of reflux esophagitis, which should be considered in the clinical treatment.
出处
《医学综述》
2016年第24期4930-4931,4939,共3页
Medical Recapitulate
关键词
反流性食管炎
幽门螺杆菌
相关性
Reflux esophagitis
Helicobacter pylori
Correlation
