摘要
目的评估我国居民经大米摄入无机砷的暴露水平及其健康风险。方法系统检索PubMed、 CNKI等数据库中2001—2020年发表文献中关于我国大米无机砷含量数据,结合2012年中国居民营养与健康状况监测数据,采用半参数蒙特卡罗模拟法估计我国居民经大米的无机砷摄入量水平;采用目标风险系数法、终生癌症风险法对居民经大米摄入无机砷产生的健康风险进行评估。结果我国各地大米中无机砷含量范围为0.038~0.1 mg/kg。我国居民经大米的无机砷暴露平均水平整体呈现出南方高于北方的特点(P<0.05),尤其是南方的江西[1.00、0.59、0.48μg/(kg·BW·d)]、湖南[0.58、0.39、0.38μg/(kg·BW·d)]、广西[0.57、0.40、0.34μg/(kg·BW·d)]等省及自治区暴露水平较高。对各省、市及自治区不同年龄段人群的风险评估结果表明,大米高消费人群的无机砷暴露可能有健康风险,其中以江西、湖南等省份的2~17岁居民中大米高消费人群(P95)的风险较高。各省、市及自治区THQ值范围为0.08~6.96,LCR值范围为0.38×10;~3.13×10;。结论经大米摄入无机砷对我国居民中的大米高消费人群可能产生一定的健康风险。
Objective To evaluate the exposure level and health risk of inorganic arsenic ingested by rice in Chinese residents. Methods The data of inorganic arsenic content in rice published in PubMed, CNKI and other databases from 2001 to 2020 were systematically retrieved. Combined with the monitoring data of nutrition and health status of Chinese residents in 2012, the inorganic arsenic intake level of Chinese residents through rice was estimated by semi parametric Monte Carlo simulation. Target hazard quotient method and lifetime cancer risk method were used to evaluate the health risk caused by inorganic arsenic in rice. Results The content of inorganic arsenic in rice ranged from 0.038 to 0.1 mg/kg. The average level of inorganic arsenic exposure of Chinese residents through rice was higher in the south than in the north(p<0.05), especially in Jiangxi [1.00, 0.59, 0.48 μg/(kg·BW·d)], Hunan [0.58, 0.39, 0.38 μg/(kg·BW·d)], Guangxi [0.57, 0.40, 0.34 μg/(kg·BW·d)] and other provinces and autonomous regions in the south. The risk assessment result of people of different ages in various provinces, cities and autonomous regions show that the inorganic arsenic exposure of people with high consumption of rice may have health risks, among which the risk of people with high consumption of rice(P95) is higher among residents aged 2-17 in Jiangxi, Hunan and other provinces. The THQ value range of each provinces, cities and autonomous regions is 0.08-6.96, and the LCR value range is 0.38×10;-3.13×10;. Conclusion Inorganic arsenic ingested by rice may pose a certain health risk to the high rice consumption population among Chinese residents.
作者
秦周
李依玲
刘佳琳
王彝白纳
魏晟
QIN Zhou;LI Yiling;LIU Jialin;WANG Yibaina;WEI Sheng(Department of Epidemiology and Health Statistics,School of Public Health,Tongji Medical College,Huazhong University of Science and Technology,Hubei Wuhan 430030,China;Key Laboratory of Food Safety Risk Assessment,Ministry of Health,China National Center for Food Safety Risk Assessment,Beijing 100022,China)
出处
《中国食品卫生杂志》
CSCD
北大核心
2021年第6期727-732,共6页
Chinese Journal of Food Hygiene
基金
国家重点研发计划(2018YFC1603105)。
关键词
大米
无机砷
暴露
风险评估
Rice
inorganic arsenic
expose
risk assessment
