摘要
目的探讨急性上呼吸道感染中CRP、PCT的临床应用价值。方法选择我院2019年6月至2020年8月收治的急性上呼吸道感染患儿共100例为研究对象,依据疾病类型分为细菌感染组(n=40)、支原体感染组(n=30)、病毒感染组(n=30)三组,另选择我院同期健康儿童40名作为健康对照组,统计分析四组儿童血清CRP、PCT水平、阳性情况及CRP、PCT单独与联合检测的诊断性能。结果细菌感染组、支原体感染组、病毒感染组患儿血清CRP水平、PCT阳性率均逐渐降低,差异有统计学意义(P<0.05),均显著高于健康对照组,差异有统计学意义(P<0.05);细菌感染组、支原体感染组、病毒感染组患儿的血清PCT水平、CRP阳性率均逐渐降低,差异有统计学意义(P<0.05),细菌感染组、支原体感染组患儿血清PCT水平、CRP阳性率均显著高于健康对照组,差异有统计学意义(P<0.05)。CRP+PCT联合检测的诊断敏感度显著高于CRP、PCT单独检测(P<0.05);CRP+PCT联合检测、PCT单独检测的诊断特异度均显著高于CRP单独检测,差异有统计学意义(P<0.05)。结论急性上呼吸道感染中CRP、PCT临床应用价值高。
Objective To investigate the clinical application value of CRP and PCT in acute upper respiratory tract infection.Methods A total of 100 children with acute upper respiratory tract infection who were admitted to our hospital from June 2019 to August 2020 were selected as the research subjects.According to the disease type,they were divided into three groups:the bacterial infection group(n=40),the mycoplasma infection group(n=30),and the viral infection group(n=30).Another 40 healthy children in our hospital during the same period were selected as the healthy control group.The levels of serum CRP and PCT,the positive situation and the diagnostic performances of CRP and PCT alone and combined detection were analyzed statistically in the four groups.Results The serum CRP levels and PCT positive rates of children in the bacterial infection group,the mycoplasma infection group and the viral infection group were gradually decreased,the difference was statistically significant(P<0.05),and were significantly higher than those in the healthy control group,the difference was statistically significant(P<0.05).The serum PCT levels and the positive rates of CRP in the bacterial infection group,the mycoplasma infection group and the viral infection group were gradually decreased,the difference was statistically significant(P<0.05).The serum PCT levels and CRP positive rates in the bacterial infection group and the mycoplasma infection group were significantly higher than those in the healthy control group,the difference was statistically significant(P<0.05).The diagnostic sensitivity of CRP+PCT combined detection was significantly higher than those of CRP and PCT alone tests,the difference was statistically significant(P<0.05).The diagnostic specificities of CRP+PCT combined test and PCT alone test were significantly higher than that of CRP alone test,the difference was statistically significant(P<0.05).Conclusion The clinical application value of CRP and PCT in acute upper respiratory tract infection is high.
作者
李峰
鄢青
黄良坚
LI Feng;YAN Qing;HUANG Liangjian(Department of Pediatrics,Jingdezhen Maternal and Child Health Hospital of Jiangxi Province,Jingdezhen 333000,China)
出处
《中国现代医生》
2021年第33期117-119,123,共4页
China Modern Doctor
基金
江西省景德镇市科技计划项目(20192SFZC027)。
关键词
急性上呼吸道感染
CRP
PCT
阳性
诊断性能
Acute upper respiratory tract infection
CRP
PCT
Positive
Diagnostic performance
