摘要
[目的]探讨痛风患者发病季节性特征,为痛风防治提供参考。[方法]运用集中度和圆形分布法对2015至2021年杭州市某三甲医院住院的痛风患者发病季节性进行统计分析,推算发病高峰日及高峰期。[结果]共收集痛风发病病例702例,发病集中度M=0.47,呈一定的季节性分布;圆形分布r=0.4640,s=71.0018°,α=154.76°,平均角差异具有统计学意义(Z=151.1510,P<0.001),推算平均高峰日为6月6日,平均高峰期为3月26日至8月17日,各年份发病高峰日有差异(F=7.27,P<0.05),但集中在春夏二季。不同性别(t=6.35,P<0.05)、年龄(F=9.8,P<0.05)、中医证型(F=57.18,P<0.05)发病高峰日均有差异,女性高峰日在春季,早于男性的初夏;不同年龄段发病高峰日集中在春末夏初;肝肾阴虚、湿热蕴结证发病高峰日分别在春季和夏季,痰浊阻滞证在春末夏初达高峰,瘀热阻滞证发病高峰日无明显季节相关性。[结论]杭州地区痛风患者发病具有季节性集中趋势,应在春夏季重点作好预防,加强管理。
[Objective] To explore the seasonal characteristics of gout onset and provide reference for the prevention and treatment. [Methods] By using the methods of concentration degree and circular distribution,the seasonal characteristics of gout patients in a grade-A tertiary hospital in Hangzhou from2015 to 2021 was analyzed,the peak day and period were calculated. [Results] A total of 702 cases of gout onset were collected,and the incidence concentration degree M=0.47,showed a certain seasonal distribution;circular distribution showed r=0.4640,s=71.0018°,α=154.76°,the mean angle was statistically significant(Z=151.1510,P<0.001),it calculated the average peak day was June 6 th and the average peak period was from March 26 to August 17. The peak days were different in each year(F=7.27,P<0.05),but concentrated in the spring and summer. There were differences in the peak day among different genders(t=6.35,P<0.05),ages(F=9.8,P<0.05),traditional Chinese medical(TCM) syndromes(F=57.18,P<0.05). Female peak day was in the spring,earlier than male which was in early summer. The peak day of different age groups was concentrated in late spring and early summer. The peak day of liver-kidney Yin deficiency syndrome and accumulated dampness-heat syndrome were in spring and summer respectively. The peak day of phlegm obstruction syndrome was reached in late spring and early summer,and the peak day of blockade of static blood and heat syndrome had no significant seasonal correlation. [Conclusion] The incidence of gout patients in Hangzhou has a seasonal concentration trend,so it should be focused on prevention measures and strengthen management in spring and summer.
作者
徐巧璐
黄继勇
罗慧佳
方茹璐
XU Qiaolu;HUANG Jiyong;LUO Huijia(The Second Clinical Medicine School of Zhejiang Chinese Medical University,Hangzhou(310053),China;The Second Affiliated Hospital of Zhejiang Chinese Medical University)
出处
《浙江中医药大学学报》
CAS
2021年第11期1173-1177,1183,共6页
Journal of Zhejiang Chinese Medical University
关键词
痛风
集中度
圆形分布法
季节性特征
高峰日
高峰期
中医证型
防治
gout
concentration degree
circular distribution method
seasonal characteristics
peak day
peak period
TCM syndromes
prevention and treatment
