摘要
目的:探讨腹腔镜穿孔缝合术对急性胃穿孔患者疼痛程度及胃肠激素水平的影响。方法:选取2019年6月-2020年5月本院收治的90例胃穿孔患者,按照随机数字表法分成观察组(n=45)与对照组(n=45),对照组采用传统开腹缝合术,观察组采用腹腔镜穿孔缝合术。对比两组临床指标、疼痛程度、舒适度、胃肠激素水平及C反应蛋白(CRP)水平。结果:观察组手术时间、肛门排气时间、下床活动时间、住院时间较对照组明显更优(P<0.05),术中出血量、镇痛药使用次数较对照组更少(P<0.05);观察组术后1、7 d视觉模拟评分法(VAS)评分明显低于对照组(P<0.05),舒适状态量表(GCQ)评分明显高于对照组(P<0.05);两组术后7 d胃动素(MTL)、促胃液素(GAS)水平明显提高(P<0.05),CRP水平明显降低(P<0.05),且观察组GAS、MTL水平高于对照组(P<0.05),CRP水平低于对照组(P<0.05);观察组并发症发生率较对照组更低(P<0.05)。结论:急性胃穿孔患者采用腹腔镜穿孔缝合术能够减轻患者疼痛程度,提高胃肠激素水平,减轻炎症反应,改善患者预后。
Objective:To investigate the effect of laparoscopic perforation suture on pain and gastrointestinal hormone levels in patients with acute gastric perforation.Method:Ninety patients with gastric perforation treated in our hospital from June 2019 to May 2020 were divided into observation group(n=45)and control group(n=45)by the random number table method.The control group was treated with traditional laparotomy suture and the observation group was treated with laparoscopic perforation suture.The clinical indexes,pain degree,comfort,gastrointestinal hormone levels and C-reactive protein(CRP)level were compared between the two groups.Result:The time of operation,the time of anal exhaust,the time of getting out of bed and the time of hospitalization in the observation group were significantly better than those in the control group(P<0.05),and the intraoperative blood loss and the use of analgesics in the observation group were less than those in the control group(P<0.05).The score of visual analogue scale(VAS)on the 1st and 7th day after operation in the observation group was significantly lower than that in the control group(P<0.05),and the score of comfort state scale(GCQ)in the observation group was significantly higher than that in the control group(P<0.05).On the 7th day after operation,the levels of motilin(MTL)and gastrin(GAS)in the two groups were significantly increased(P<0.05),level of CRP decreased(P<0.05);and the levels of GAS and MTL in the observation group were higher than those in the control group(P<0.05),the level of CRP in the observation group was lower than that in the control group(P<0.05),and the incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion:Laparoscopic perforation suture in patients with acute gastric perforation can reduce the degree of pain,increase the level of gastrointestinal hormones,reduce inflammatory reaction and improve the prognosis of patients.
作者
周元喜
李立新
齐孝安
ZHOU Yuanxi;LI Lixin;QI Xiao’an(Wuhan Xinzhou District People’s Hospital,Wuhan 430400,China)
出处
《中外医学研究》
2021年第30期130-133,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
腹腔镜穿孔缝合术
急性胃穿孔
疼痛程度
胃肠激素水平
Laparoscopic perforation suture
Acute gastric perforation
Pain degree
Gastrointestinal hormone level
