摘要
目的监测分析深圳市介入放射工作人员长期接触电离辐射对外周血液常规和淋巴细胞微核的影响,为介入放射工作人员的职业健康管理提供依据。方法选取深圳市2017—2018年15家三级甲等医院在本院接受职业健康检查的放射工作人员591名,其中从事介入放射学工作人员304名为介入放射组,同期X射线影像诊断工作人员287名为普通X射线组,比较分析其个人外照射剂量及外周血液常规、淋巴细胞微核率和转化率检测结果变化。结果介入放射组平均年龄为37.0(32.0,45.0)岁,男性占62.17%,人均年照射剂量为0.07(0.04,0.21) mSv。普通X射线组平均年龄为36.0(30.0,44.0)岁,男性占55.40%,人均年照射剂量为0.03(0.03,0.05) mSv。人均年照射剂量在两组间差异有统计学意义(W=21 676,P=0.000)。两组的白细胞总数、淋巴细胞百分比、中性粒细胞百分比和淋巴细胞微核率之间差异有统计学意义(均P<0.05)。随着放射工龄的增长,介入放射组淋巴细胞微核率和异常检出率均增高,差异有统计学意义(均P<0.05),而随着放射工龄的增长,对介入放射组血细胞数影响不明显。结论深圳市介入放射工作人员受照射剂量水平较低,但其淋巴细胞微核异常检出率随着放射工龄的增长出现明显增高的趋势,需进一步加强对介入放射工作人员职业健康管理,提高个人防护意识,将其接受辐射损伤的程度降到最低,保证身体健康与职业安全。
Objective To monitor and analyze the influence of long-term ionizing radiation exposure on peripheral blood cell count and lymphocyte micronucleus among interventional radiation workers in Shenzhen City, and to provide a basis for occupational health management of interventional workers with radiation exposure. Methods We recruited 591 radiation workers from 15 first-class grade A hospitals in Shenzhen City from 2017 to 2018, and all of them underwent health check-ups in Shenzhen Prevention and Treatment Center for Occupational Diseases. Among them, 304 interventional radiation workers were selected into the interventional radiation group, and 287 X-ray imaging diagnosis workers served as the general X-ray group at the same time. We compared and analyzed their personal external radiation exposure dose, peripheral blood cell counts and lymphocyte micronucleus rate and conversion rate. Results The average age of the interventional radiation group was 37.0(32.0, 45.0) years, the males accounted for 62.17%, and the annual effective dose per-capital was 0.07(0.04, 0.21) mSv. The average age of the general X-ray group was 36.0(30.0, 44.0) years, the males accounted for 55.40%, and the annual effective dose per-capital was 0.03(0.03, 0.05) mSv. There was a statistically significant difference in the annual effective dose per-capital between the two groups(W=21,676, P=0.000). In the total white blood cell count, lymphocyte percentage, neutrophil percentage, and lymphocyte micronucleus rate, the results showed statistically significant differences for the comparison between the two groups(all P<0.05). With the increase of radiation working years, the lymphocyte micronucleus rate and abnormal detection rate in the interventional radiation group both increased, showing statistically significant differences(both P<0.05), but the changes of blood cell count in the interventional radiation group were not statistically significant. Conclusion The radiation dose of the interventional radiation workers in Shenzhen City is relatively low,but their lymphocyte micronucleus rate and abnormal detection rate show significantly increasing trends with radiation working years. It is necessary to further enhance the interventional radiation workers’ occupational health management and improve their personal protection awareness so as to lower the level of radiation damage to the minimum and ensure their health and occupational safety.
作者
刘征宇
高朝贤
李丽梅
张怡
张志敏
林大枫
LIU Zheng-yu;GAO Chao-xian;LI Li-mei;ZHANG Yi;ZHANG Zhi-min;LIN Da-feng(Institute of Pathology and Toxicology,Shenzhen Prevention and Treatment Center for Occupational Diseases,Shenzhen,Guangdong 518020,China)
出处
《实用预防医学》
CAS
2021年第11期1307-1310,共4页
Practical Preventive Medicine
基金
深圳市科技创新计划项目(JCYJ20170307145422811)
深卫计科教【2017】57号(SZFZ2017089)
深圳市医学重点学科2020-2024建设经费项目(SZGSP015)
深圳市卫生计生系统科研项目(SZFZ2017092)。
关键词
介入放射
个人剂量
血细胞
淋巴细胞
微核
电离辐射
interventional radiation
individual dose
blood cell
lymphocyte
micronucleus
ionizing radiation
