摘要
近年来,从肠到脑的信号通路作为缺血性脑卒中不可忽视的影响因素而备受关注,肠道菌群参与缺血性脑卒中高危致病因素的生成。中医认为脑与肠腑在生理上通过经络密切联系,功能上相互滋养、相互调节;在病理上,脑病可及肠腑,肠病可及脑腑,二者相互影响。基于此可将调控肠道菌群趋于稳定作为研究缺血性脑卒中治疗方法的切入点,目前,包括中药活性成分、中药单体、中药复方以及针灸等在内的中医药治疗方法,通过调控肠道菌群改善缺血性脑卒中的发生、发展及预后已取得一定进展,本文对中医药基于肠道菌群防治缺血性脑卒中进行综述。
In recent years,the signaling pathway from the intestine to the brain has attracted much attention as a non-negligible influencing factor in ischemic stroke.Intestinal flora is involved in the generation of high-risk pathogenic factors in ischemic stroke.Traditional Chinese medicine believes that the brain and intestines are closely connected physiologically through the meridians,and functionally they nourish and regulate each other;pathologically,encephalopathy may affect the intestines,and intestinal diseases may affect the brain,and the two influence each other.Based on this understanding,the regulation of intestinal flora stabilization can be used as an entry point to study the treatment of ischemic stroke.At present,the treatment methods of traditional Chinese medicine including the active ingredients of traditional Chinese medicine,the monomer of traditional Chinese medicine,the compounds of traditional Chinese medicine and acupuncture are adopted.Some progress has been made in regulating the intestinal flora to improve the occurrence,development and prognosis of ischemic stroke.This article reviews the prevention and treatment of ischemic stroke based on intestinal flora in traditional Chinese medicine.
作者
韦亮
祝美珍
孙诗杰
俞睿
曾宪晶
Wei Liang;Zhu Meizhen;Sun Shijie;Yu Rui;Zeng Xianjing(Guangxi University of Chinese Medicine,Guangxi 530001)
出处
《现代中医临床》
2021年第5期72-76,共5页
Modern Chinese Clinical Medicine
基金
国家自然科学基金资助项目(No.81460725)
广西中医药大学校级重点硕士研究生科研创新项目(No.YCSZ2020016)。
关键词
中医药
肠道菌群
缺血性脑卒中
综述
traditional Chinese medicine
intestinal flora
ischemic stroke
review
