摘要
目的分析间歇性断食(IF)法对2型糖尿病(T2MD)患者糖脂代谢指标的影响。方法前瞻纳入新乡市中心医院2019年5月至2020年10月就诊的144例T2MD患者为研究对象,根据患者入院单单双号将其分为对照组、研究组,各72例;两组均接受T2MD常规治疗,治疗期间对照组接受常规饮食管理干预,研究组在常规饮食管理基础上接受IF法干预,均干预3个月;于干预前、干预3个月,记录并比较两组体重指数(BMI)、检测并比较两组血糖水平[空腹血糖(FPG)、餐后2 h血糖(2h PG)、糖化血红蛋白(HbA1c)]、血脂水平[总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)]。结果两组干预前BMI、血糖水平、血脂水平比较,差异均无统计学意义(P>0.05);干预3个月,研究组BMI低于对照组(P<0.05);干预3个月,研究组FPG、2h PG、HbA1c、TC、TG、LDL水平均低于对照组,HDL水平高于对照组(P<0.05)。结论T2MD患者采用IF法干预,利于减轻患者BMI,改善糖脂代谢指标。
【Objective】To analyze the effect of intermittent fasting(IF)method on indexes of glucose and lipid metabolism in patients with type 2 diabetes mellitus(T 2 MD).【Methods】A total of 144 patients with T 2 MD admitted to Xinxiang Central Hospital from May 2019 to October 2020 were prospectively included as the study subjects,the patients were divided into a control group and a study group according to the odd and even numbers of their admission number,72 cases in each group;both groups received routine treatment of T 2 MD,the control group received routine diet management intervention,while the study group received IF intervention on the basis of routine diet management during treatment,both were intervened for 3 months;before intervention and 3 months after intervention,the body mass index(BMI)of the two groups were recorded and compared,the levels of blood glucose[fasting plasma glucose(FPG),2-hour postprandial blood glucose(2 h PG),glycosylated hemoglobin(HbA 1 c)]and blood lipid[total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL),high density lipoprotein(HDL)]were detected and compared between the two groups.【Results】There was no statistical significant difference in BMI,blood glucose level and blood lipid level between the two groups before intervention(P>0.05);after 3 months of intervention,the BMI of the study group was lower than that of the control group(P<0.05);after 3 months of intervention,the levels of FPG,2 h PG,HbA 1 c,TC,TG and LDL in the study group were lower than those in the control group,while the level of HDL was higher than that in the control group(P<0.05).【Conclusion】IF intervention is conductive to reducing BMI and improving indexes of glucose and lipid metabolism in patients with T 2 MD.
作者
陈玉凤
赵建林
周艳红
CHEN Yufeng;ZHAO Jianlin;ZHOU Yanhong(Department of Endocrinology,Xinxiang Central Hospital(The Fourth Clinical College of Xinxiang Medical University),Xinxiang,Henan 453000,China)
出处
《中国医学工程》
2021年第10期51-55,共5页
China Medical Engineering
基金
2019年河南医学科技攻关计划(联合共建)项目(LHGJ20191331)。
关键词
2型糖尿病
间歇性断食法
饮食管理
体重指数
血糖水平
血脂水平
type 2 diabetes mellitus
intermittent fasting method
diet management
body mass index
blood glucose level
blood lipid level
