摘要
轻型卒中和短暂性脑缺血发作(transient ischemic attack,TIA)患者早期复发或恶化的风险很高。抗血小板治疗已被公认可以降低缺血性血管事件风险,各指南均推荐对缺血性卒中患者进行抗血小板治疗。双重抗血小板治疗(dual antiplatelet therapy,DAPT)是指应用2种不同作用机制的药物阻断血小板聚集,防止血栓形成。DAPT有多种组合,其安全性和有效性仍存在不确定性。文章对DAPT在轻型卒中和TIA患者中的有效性和安全性进行了综述。
Patients with mild stroke and transient ischemic attack(TIA)have a high risk of early recurrence or deterioration.Antiplatelet therapy has been recognized to reduce the risk of ischemic vascular events.All guidelines recommend antiplatelet therapy for patients with ischemic stroke.Dual antiplatelet therapy(DAPT)refers to the application of two drugs with different mechanisms to block platelet aggregation and prevent thrombosis.There are many combinations of DAPT,and its safety and effectiveness are still uncertain.This article reviews the efficacy and safety of DAPT in patients with mild stroke and TIA.
作者
崔倩倩
王玉芬
Cui Qianqian;Wang Yufen(Department of Neurology,Heping Hospital Affiliated to Changzhi Medical College,Changzhi 046000,China)
出处
《国际脑血管病杂志》
2021年第7期514-520,共7页
International Journal of Cerebrovascular Diseases
