摘要
目的探讨大黄醒神汤灌肠治疗肝性脑病的疗效。方法回顾性研究于2019年1月至2020年6月我院进行治疗的肝性脑病患者60例作为研究对象,根据治疗方法不同分为两组,每组各30例。对照组采用常规西药治疗,给予观察组大黄醒神汤灌肠治疗。比较治疗后两组患者的症状积分、血氨水平、清醒时间及不良反应发生率。结果观察组用药后症状积分高于对照组(P<0.05);观察组用药后血氨水平低于对照组,观察组治疗后清醒时间短于对照组(P<0.05);治疗后观察组患者出现皮疹、瘙痒、乏力、休克的总发生率为6.67%,低于对照组的26.67%(P<0.05)。结论大黄醒神汤灌肠治疗肝性脑病效果较好,可有效改善患者的临床症状,降低血氨水平,减少清醒时间及不良反应发生情况,值得推广应用。
Objective To investigate the efficacy of enema with Dahuang Xingshen Decoction in the treatment of hepatic encephalopathy.Methods A total of 60 patients with hepatic encephalopathy treated from January 2019 to June 2020 were selected as the study subjects for a retrospective study.All patients were divided into the control group and the observation group according to the different treatment methods,with 30 patients in each group.The control group was treated with conventional western medicine,while the observation group was treated with enema with Dahuang Xingshen Decoction.The symptom scores,blood ammonia levels,recovery time and incidences of adverse reactions of the patients in the two groups were compared after treatment.Results After treatment,the symptom scores in the observation group were higher than in the control group(P<0.05).The blood ammonia level in the observation group was lower than that in the control group after treatment,with statistically significant difference(P<0.05).The recovery time in the observation group was shorter than that in the control group after treatment,with statistically significant difference(P<0.05).The total incidence of rash,pruritus,fatigue and shock in the observation group was 6.67%,which was lower than that of 26.67%in the control group,with statistically significant difference(P<0.05).Conclusion The enema with Dahuang Xingshen Decoction shows a good efficacy in treating hepatic encephalopathy,which can effectively improve the clinical symptoms and reduce blood ammonia level,as well as shorten the recovery time and the incidence of adverse reactions.Therefore,it is worthy of promotion and application.
作者
吴小卫
何倩丹
WU Xiaowei;HE Qiandan(Department of Internal MedicineⅡ,Gaoming Hospital of Traditional Chinese Medicine in Foshan City,Guangdong,Foshan 528500,China)
出处
《中国医药科学》
2021年第14期64-66,共3页
China Medicine And Pharmacy
基金
广东省佛山市卫生健康局医学科研课题(20210448)。
关键词
大黄醒神汤
灌肠治疗
肝性脑病
血氨水平
不良反应
疗效
Dahuang Xingshen Decoction
Enema treatment
Hepatic encephalopathy
Blood ammonia level
Adverse reactions
Efficacy
