摘要
目的探讨CT扫描联合血清AFP-L3、CEA在诊断肝细胞癌(HCC)中的应用价值,为提高肝细胞癌患者的诊断率提供理论依据。方法选取2019年1月~2020年3月于我院及南方医院本部诊治的肝脏占位性病变患者200例,根据术后病理分为HCC组和非HCC组,记录患者一般临床资料,对比分析CT、AFP-L3、CEA及三者联合检查与病理结果的符合率、特异度、灵敏度、阳性预测值、阴性预测值等指标差异。结果HCC组患者血清AFP-L3、CEA水平明显高于非HCC组,差异具有统计学意义(P<0.05);CEA诊断符合率明显低于CT、AFP-L3诊断符合率,差异具有统计学意义(P<0.05);联合检查特异度、PPV、NPV均高于单独检查方式,差异具有统计学意义(P<0.05)。结论CT扫描联合血清AFP-L3、CEA能够提高肝细胞癌诊断率,具有较好的临床应用价值。
Objective To analyze the application value of CT scan combined with serum AFP-L3 and CEA in the diagnosis of HCC,so as to provide theoretical basis for improving the diagnosis rate of HCC.Methods From January 2019 to March 2020,200 patients with liver space occupying lesions were included in our hospital.According to the postoperative pathology,they were divided into HCC group and non HCC group.The general clinical data of the patients were recorded and the coincidence rate,specificity,sensitivity,positive predictive value and negative predictive value of CT,AFP-L3,CEA and their combined examination and pathological results were compared and analyzed.Results The levels of AFP-L3 and CEA in HCC group were significantly higher than those in non HCC group,the difference was statistically significant(P<0.05);the diagnostic coincidence rate of CEA was significantly lower than that of CT and AFP-L3,the difference was statistically significant(P<0.05);the specificity,PPV and NPV of combined examination were higher than those of single examination,the difference was statistically significant(P<0.05).Conclusion CT scan combined with serum AFP-L3 and CEA can improve the diagnosis rate of HCC,which has better clinical application value.
作者
黄伟康
文戈
吴水天
钟金城
洪静静
HUANG Weikang;WEN Ge;WU Shuitian;ZHONG Jincheng;HONG Jingjing(Imaging Department, Zengcheng Branch Of Nanfang Hospital, Southern Medical University, Guangzhou 511340, P.R.China)
出处
《医学影像学杂志》
2021年第5期810-813,共4页
Journal of Medical Imaging
基金
广东省医学科学技术研究基金项目(编号:C2019077)。
关键词
肝细胞癌
体层摄影术
X线计算机
癌胚抗原
甲胎蛋白异质体
诊断
Hepatocellular carcinoma
Tomography,X-ray computed
Carcinoembryonic antigen
Alpha fetoprotein-L3
Diagnosis
