摘要
造影剂急性肾损伤(CI-AKI)是指在行血管造影或其他医疗过程中使用造影剂后所导致的急性肾功能损伤。随着冠脉介入治疗和放射诊断技术在临床的广泛应用,造影剂也随之进行广泛的应用,成为既低灌注和药物性肾损伤之后引起院内急性肾损伤的第三大病因。CI-AKI的发病机制尚不清楚,在临床上无有效的治疗方案,现阶段多采用水化疗法进行预防。该文将对CI-AKI的定义、发病机制、危险因素、早期预测指标、防范治疗等研究作一综述。
Contrast-induced acute kidney injury (CI-AKI) is defined as acute renal injury caused by the use of contrast agents during angiography or other medical procedures.With the continuous development of of coronary interventional therapy and radiological diagnosis technology,contrast agents have also been widely used,becoming the main cause of nosocomial acute kidney injury after both hypoperfusion and drug-induced kidney injury.The pathogenesis of CI-AKI is still unclear,there is no effective treatment in clinical practice,and hydration therapy is mostly used for prevention at this stage.In this paper,the authors will review the definition,pathogenesis,risk factors,early predictors,and preventive treatment of CI-AKI.
作者
赵鑫
郑萍萍
肖融
程盛荣
李雪艳
邓大同
ZHAO Xin;ZHENG Ping-ping;XIAO Rong(The First Clinical Medical College of Anhui Medical University,Hefei 230022,Anhui;The First Affiliated Hospital of Anhui Medical University,Hefei 230022,Anhui)
出处
《安徽卫生职业技术学院学报》
2021年第2期35-37,共3页
Journal of Anhui Health Vocational & Technical College
基金
2017年安徽医科大学第一附属医院博士基金1313号。
关键词
造影剂肾病
发病机制
防范措施
预测指标
contrast-induced nephropathy
pathogenesis
preventive measures
predictive indicators
