摘要
围产期奶牛脂肪肝等营养代谢性疾病的防治和调控是提高生产性能和效益的关键。胆碱作为一种动物生长发育必需的营养素,在奶牛肝脏脂肪代谢调控方面发挥着重要的作用。饲粮中适当补充胆碱可以有效降低肝脏脂肪含量和预防脂肪肝,并维持肝脏的正常生理功能。胆碱主要通过上调脂肪分解和下调脂肪生成途径的基因和蛋白的表达水平来调节脂肪代谢,从而减少脂肪沉积,缓解脂肪肝。本研究在已有文献报道基础上,阐述了胆碱的特性和功能,围绕胆碱对动物肝脏脂肪代谢的调节作用及机制进行了综述,旨在为奶牛维持机体健康、提高反刍动物生产性能提供理论依据。
In the production and breeding process of the dairy industry,the prevention and control of nutritional metabolic diseases,such as fatty liver in perinatal dairy cows,is key to improved performance and production efficiency.Choline,an essential nutrient for animal growth and development,plays an important role in the regulation of liver fat metabolism.Proper dietary supplementation of choline can effectively reduce liver fat content,prevent fatty liver,and maintain the normal physiological function of the liver.Choline regulates lipid metabolism by up-regulating and down-regulating the expression of genes and proteins of the lipolysis and adipogenesis pathways,thus reducing fat deposition and alleviating fatty liver.In this study,the characteristics and functions of choline and its regulatory effect and mechanism on liver fat metabolism in dairy cows were reviewed.The study aimed to provide a theoretical basis for maintaining body health of dairy cows and improve ruminant production performance.
作者
刘喆佳
王弘浩
姚军虎
曹阳春
LIU Zhejia;WANG Honghao;YAO Junhu;CAO Yangchun(College of Animal Science and Technology,Northwest A&F University,Yangling 712100,Shaanxi,China)
出处
《草业科学》
CAS
CSCD
北大核心
2021年第4期776-784,共9页
Pratacultural Science
基金
国家自然科学基金项目(31972592)
陕西省重点研发计划项目(2021NY-019)
榆林市科技计划项目(CXY-2020-075)。
关键词
胆碱
奶牛
围产期
脂代谢
机理
choline
dairy cows
perinatal
fat metabolism
mechanism
