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具核梭杆菌与炎症性肠病相关性的研究进展 被引量:5

Research advances on the relationship between fusobacterium nucleatum and inflammatory bowel disease
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摘要 炎症性肠病(IBD)是一种慢性非特异性肠道炎症性疾病,由肠道菌群紊乱、宿主免疫、环境、遗传易感性等多种因素综合作用所致。近年来,我国IBD患病率逐年上升,且肠道菌群紊乱与IBD的关系受到越来越多的关注。研究表明,具核梭杆菌(F.nucleatum)可通过参与破坏肠黏膜屏障完整性、参与肠道免疫调节及与其他微生物相互作用,引发或加重肠道炎症反应。本文对F.nucleatum与IBD相关性的研究进展作一综述,以期为IBD的诊治提供新思路。
作者 陆世珉 魏舒纯 董卫国 Lu Shimin;Wei Shuchun;Dong Weiguo
出处 《临床内科杂志》 CAS 2021年第4期217-219,共3页 Journal of Clinical Internal Medicine
基金 湖北省第二届领军人才项目。
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