摘要
目的:探讨常规MRI纹理分析鉴别骨巨细胞瘤(GCT)与动脉瘤样骨囊肿(ABC)的价值。方法:回顾性分析经手术病理证实的16例GCT和13例ABC的MRI图像资料。分析2种肿瘤的MRI形态特征,在MRI图像上手动勾画感兴趣区(ROI)、提取纹理特征。利用受试者工作特征曲线(ROC)及Logistic回归分析法评估MRI形态特征、纹理参数及模型的诊断效能。结果:2种肿瘤的形态特征中肿瘤囊性变、液-液平面、纤维间隔、周围骨髓水肿间差异有统计学意义,鉴别2种肿瘤曲线下面积(AUC) 0.110~0.690,构建的形态特征模型鉴别2种肿瘤的AUC值为0.708。AK软件从FSPdWI中最终筛选获得价值较大的纹理参数,鉴别2种肿瘤效能AUC值0.359~0.703,构建的纹理参数模型鉴别2种肿瘤的AUC值为0.713,进一步构建形态特征与纹理参数联合模型鉴别2种肿瘤的效能AUC值0.890,周围骨髓水肿和长游程低灰阶显著性为独立预测因子。结论:MRI形态特征及纹理参数模型对于GCT和ABC的鉴别均具有一定的价值,两者联合能进一步提高诊断效能,是常规MRI鉴别诊断困难时一个值得选择的方法。
Objective:To explore the value of MRI texture analysis in differential diagnosis of giant cell tumor of bone(GCT)and aneurismal bone cyst(ABC).Methods:The MRI image data of 16 cases with GCT and 13 cases with ABC confirmed by operation and pathology were retrospectively analyzed.Based on the MRI morphological features of the two kinds of tumors,the region of interest(ROI)on the MRI image was delineated,and the texture features were analyzed.The receiver operating characteristic curve(ROC)and logistic regression analysis were used to evaluate the MRI morphological features,texture parameters and the diagnostic efficacy of the model.Results:The morphological characteristics of the two tumors were statistically different in tumor cystic degeneration,fluid-liquid level,fibrous septum,and peripheral bone marrow edema(P<0.05).The areas under ROC curve(AUC)of the two tumors were 0.110-0.690,and the AUC value of the constructed morphological model was 0.708.The AK software finally screened 9 valuable texture parameters from FSPdWI,with an AUC value of 0.359-0.703.The texture parameter model was constructed with an AUC value of 0.713,and the model of morphological feature combined with texture parameter was constructed with an AUC value of 0.890.Peripheral bone marrow edema and long-run low-gray scale significance were independent predictors.Conclusions:The models of morphological features and texture parameters of MRI have values for the differentiation of GCT and ABC.The combination of the two models can further improve the diagnostic efficiency and is a method worth choosing when the conventional MRI differential diagnosis is difficult.
作者
吴莉莉
陈基明
邵颖
李周丽
丁俊
WU Lili;CHEN Jiming;SHAO Ying;LI Zhouli;DING Jun(Medical Imaging Center,Yijishan Hospital,Wannan Medical College,Wuhu 241001,China)
出处
《沈阳医学院学报》
2021年第2期132-136,共5页
Journal of Shenyang Medical College
关键词
骨巨细胞瘤
动脉瘤样骨囊肿
纹理分析
磁共振成像
giant cell tumor of bone
aneurismal bone cyst
texture analysis
magnetic resonance imaging
