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贮存式自身输血在Rh(D)阴性妊娠晚期孕妇中的应用探讨

Application of predeposited autologous blood transfusion in late pregnancy of Rh(D)negative pregnant women
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摘要 目的探讨贮存式自身输血在Rh(D)阴性孕妇中的应用情况。方法对54例Rh(D)阴性孕妇,在预产期前1~3周采集自体血200~400 mL,待分娩时或分娩后回输。分析采血前后孕妇血压,脉搏,胎心变化;采血前后以及自体血液回输前后孕妇的红细胞(RBC)、血红蛋白(Hb),红细胞压积(Hct),血小板(Plt)等指标变化。观察输血后及产后母亲情况及新生儿Apgar评分。结果54例孕妇采血后收缩压比采血前低(P<0.05),舒张压、脉搏、胎心等,采血前后差异无统计学意义(P>0.05)。采血后Hb、Hct低于采血前,差异有统计学意义(P<0.05),RBC、PLT差异无统计学意义(P>0.05)。19例患者进行了自体血回输,无任何输血不良反应发生,回输前、回输后3 d的RBC、Hb、Hct、PLT结果差异无统计学意义(P>0.05)。新生儿Apgar评分均在9~10分。结论晚期妊娠贮存式自身输血不仅解决了Rh(D)阴性孕妇血源紧张问题,且对母婴不会造成危险,是一种安全有效的输血方式,值得推广。 Objective To investigate the application of predeposited autologous blood transfusion in late pregnancy of Rh(D)negative pregnant women.Methods For 54 Rh(D)-negative blood type pregnant women,200~400ml of autologous blood was collected 1 to 3 weeks before the expected date of delivery,and then reinfused during or after delivery.Analyze the changes of blood pressure,pulse and fetal heart rate before and after blood collection,The red blood cell index such as red blood cells(RBC),hemoglobin(Hb),hematocrit(Hct),platelet(Plt)were analyzed before and after blood collection,before and after autologous blood transfusion respectively.The outcomes of autotransfusion and the postpartum pregnant women and Apgar score of infant were observed.Results The systolic blood pressure of 54 pregnant women after blood collection was lower than that of before blood collection(P<0.05).There was no significant difference in diastolic blood pressure,pulse and fetal heart rate before and after blood collection(P>0.05).After blood collection,Hb and HCT were lower than before blood collection,the difference was statistically significant(P<0.05),and the difference between RBC and PLT was not statistically significant(P>0.05).19 women have successfully undergone autotransfusion without any adverse reactions of transfusion,There was no significant difference in the results of RBC,Hb,HCT and PLT before and 3 days after reinfusion(P>0.05).The Apgar scores of infants are all 9-10.Conclusion Preoperative autologous blood donation has no ill influence on maternal and infants,It is an effective method to solve the problem of blood shortage of Rh(D)negative pregnant women,thererfor,it is worth promoting.
作者 周小婷 魏寿忠 Zhou Xiaoting;Wei Shouzhong(The Ningde Municipal Hospital Affiliated to Ningde Teachers College,Ningde,Fujian 352100)
出处 《基层医学论坛》 2021年第8期1108-1110,共3页 The Medical Forum
关键词 妊娠晚期 RH(D)阴性 贮存式自身输血 应用分析 Late pregnancy Rh(D)negative blood type Predeposited autologous blood transfusion Application analysis
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