摘要
目的:探讨比索洛尔联合胺碘酮对快速型心律失常患者血液流变学及心率变异性的影响。方法:选择某院收治的快速型心律失常患者76例,按照随机数表法分为2组,每组38例。对照组患者接受胺碘酮治疗,观察组患者在此基础上联合比索洛尔治疗。观察2组患者临床疗效、血液流变学及心率变异性指标〔包括平均正常RR间期的标准差(SDNN)、正常RR间期标准差的平均值(SDANN)、相邻RR间期差的均方根(RMSSD)、相邻RR间期差值>50 ms的百分数(PNN50)〕的变化。结果:观察组患者治疗有效率、SDNN、SDANN、RMSSD及PNN50水平均高于对照组(P<0.05);观察组治疗后全血高切黏度、全血低切粘度、纤维蛋白原及血浆粘度均低于对照组(P<0.05)。结论:比索洛尔联合胺碘酮应用于快速型心律失常的治疗疗效较佳,能够有效改善患者的血液流变学及心率变异性指标。
Objective:To investigate the effect of bisoprolol combined with amiodarone on hemorheology and heart rate variability in patients with tachyarrhythmia.Methods:76 patients with tachyarrhythmia were randomly divided into two groups,with 38 cases in each.The control group received amiodarone treatment,and the observation group was treated with bisoprolol on the basis of the above therapy.The therapeutic effect,hemorheology and heart rate variability of the two groups were observed.Results:Compared with the control group,the total effective rate of the observation group was higher(P<0.05).SDNN,SDANN,RMSSD and PNN50 levels in the observation group were also higher than those in the control group(P<0.05).After the treatment,the whole blood viscosity,fibrinogen and plasma viscosity of the observation group were lower than those of the control group(P<0.05).Conclusion:Bisoprolol combined with amiodarone is effective in the treatment of patients with tachyarrhythmia.
作者
司晓敏
SI Xiaomin(Department of Cardiovascular Medicine,The Second People's Hospital of Xiayi County,Henan 476400,China)
出处
《淮海医药》
CAS
2020年第6期574-576,共3页
Journal of Huaihai Medicine
