摘要
目的:探讨血栓通联合阿司匹林治疗急性脑梗死及对S-100β蛋白、t-PA和神经功能的影响。方法:对某院收治的86例急性脑梗死患者随机分为观察组和对照组各43例。对照组通过阿司匹林肠溶片进行治疗,观察组在对照组基础上联合血栓通进行治疗,对比两组临床疗效以及对S-100β蛋白、t-PA和神经功能的影响。结果:观察组总有效率高于对照组,并发症发生率低于对照组,差异具有统计学意义(P<0.05);治疗后,两组MoCA评分、WMS评分、D-二聚体、PAI-1、TM、S-100β蛋白、t-PA、NIHSS评分以及ADL评分均和治疗前相比有明显差异,且组间差异明显,均具有统计学意义(P<0.05)。结论:血栓通联合阿司匹林治疗急性脑梗死具有良好的临床疗效,提高认知水平和生活质量,且安全性较高,无严重不良反应,值得推广应用。
Objective:To investigate the effects of Xueshuantong combined with aspirin in the treatment of acute cerebral infarction and its effect on S-100βprotein,t-PA and nerve function.Methods:86 patients with acute cerebral infarction in a hospital were randomly divided into observation group and control group,with 43 cases in each group.The control group was treated with aspirin enteric-coated tablets,and the observation group was treated with Xueshuantong on the basis of the control group.The clinical efficacy and the effects on S-100βprotein,t-PA and nerve function were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,and the incidence of complications was lower than that of the control group.The difference was statistically significant(P<0.05).Compared with before treatment,there were significant differences in MoCA scores,WMS scores,D-dimers,PAI-1,TM,S-100βproteins,t-PA,NIHSS scores and pre-treatment scores in the two groups after treatment,and the differences between the two groups were also obvious,with statistical significace(P<0.05).Conclusion:Xueshuantong combined with aspirin has a good clinical effect in the treatment of acute cerebral infarction,which can improve cognition and quality of life,with high safety,without serious adverse reactions,and is worthy of promotion and application.
作者
孙海蛟
Sun Haijiao(Department of Neurology,Changyuan County People's Hospital,Xinxiang 453400)
出处
《数理医药学杂志》
2021年第1期71-73,共3页
Journal of Mathematical Medicine
