摘要
目的分析新型冠状病毒肺炎(COVID-19)确诊病例及临床诊断病例的临床特点,为COVID-19的诊疗提供依据。方法收集2020年1月—2月收治的24例COVID-19确诊病例和16例临床诊断病例分别纳入确诊组和临床诊断组,分析和比较2组的临床表现、实验室检测指标以及影像学特点。结果确诊组和临床诊断组主要临床表现均为发热(分别为54.17%和68.75%)、咳嗽(分别为83.33%和56.25%)和纳差、乏力(分别为25.00%和25.00%)。部分临床诊断组(31.25%)以消化道症状为主要临床表现。2组早期实验室检测指标均表现为白细胞计数正常或减少、淋巴细胞计数减少、C反应蛋白升高;部分患者出现肝功能异常、凝血功能异常或心肌酶升高。2组入院1周后均出现明显的血清白蛋白水平的下降(P<0.01,P<0.05)。影像学特点主要表现为双肺多发的、靠近胸膜下的斑片状、磨玻璃样影。结论COVID-19确诊病例和临床诊断病例临床表现、实验室检测指标、影像学表现相似。对于临床诊断患者,为有效控制疾病进展,可给予及时的隔离及治疗。
Objective To analyze the clinical characteristics of confirmed cases and clinically diagnosed cases of corona virus disease 2019(COVID-19),thereby providing basis for the diagnosis and treatment of COVID-19.Methods 24 confirmed cases of COVID-19 and 16 clinically diagnosed cases admitted from January 2020 to February 2020 were collected and included into the confirmation group and the clinical diagnosis group,respectively.The clinical manifestations,laboratory tests and imaging characteristics of the two groups were analyzed and compared.Results The main clinical manifestations were fever(54.17%vs.68.75%respectively),cough(83.33%vs.56.25%respectively),poor appetite and fatigue(25.00%vs.25.00%respectively)in the confirmation group and the clinical diagnosis group.In some clinical diagnosis groups(31.25%),digestive tract symptoms were the main clinical manifestations.The early laboratory test indicators in both groups were normal or decreased white blood cell count,decreased lymphocyte count and increased C-reactive protein.Some patients had abnormal liver function,abnormal coagulation function or elevated myocardial enzymes.There was a significant decrease in serum albumin level in both groups at 1 week after admission(P<0.01,P<0.05).The main imaging features were multiple patchy,ground-glass opacities near the pleura in both lungs.Conclusion The clinical manifestations,laboratory test indicators and imaging findings of confirmed and clinically diagnosed COVID-19 cases were similar.For clinically diagnosed patients,timely isolation and treatment can be given in order to effectively control disease progression.
作者
龚玖瑜
俞东
凡蓉
保鹏涛
姜林
GONG Jiu-yu;YU Dong;FAN Rong;BAO Peng-tao;JIANG Lin(the First Department of Internal Medicine,Hubei Armed Police Corps Hospital,Wuhan 430061,China;Department of Respiration,the 8th Medical Center of PLA General Hospital,Beijing 100093,China)
出处
《解放军医药杂志》
CAS
2020年第12期54-58,共5页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
军队医学科技青年课题(17QNP034)。
