摘要
目的探讨中风后癫痫患者采用丙戊酸钠药物治疗的临床价值。方法 92例中风后癫痫患者,根据随机数字表法分为观察组与对照组,每组46例。对照组给予常规治疗,观察组在对照组基础上运用丙戊酸钠治疗。比较两组癫痫发作情况、神经功能缺损情况、生活质量评分。结果观察组的癫痫发作率为4.34%,低于对照组的19.57%,差异有统计学意义(P<0.05)。治疗后,观察组神经功能缺损情况优于对照组,差异有统计学意义(P<0.05)。观察组的生理职能(PF)、生理职能(RP)、躯体疼痛(BP)、总体健康(GH)、活力(VT)、社会功能(SF)、情感职能(RE)、精神健康(MH)评分均高于对照组,差异有统计学意义(P<0.05)。结论临床上运用丙戊酸钠对中风后癫痫患者进行治疗,不仅可以减少癫痫发作,还能改善患者预后。
Objective To discuss the clinical value of sodium valproate in the treatment of patients with epilepsy after stroke.Methods A total of 92 patients with epilepsy after stroke were divided into observation group and control group according to random numerical table,with 46 cases in each group.The control group received conventional therapy,and the observation group received sodium valproate on the basis of the control group.The epileptic seizures,neurological deficits,and quality of life scores were compared between the two groups.Results The seizures rate of the observation group was 4.34%,which was lower than 19.57%of the control group,and the difference was statistically significant(P<0.05).After treatment,the neurological deficits of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The physiological function(PF),role-physical(RP),body pain(BP),general health(GH),vitality(VT),social function(SF),responsibility of emotion(RE),mental health(MH)score of the observation group were higher than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Sodium valproate can not only reduce seizures,but also improve the prognosis of patients with epilepsy after stroke.
作者
黄翠媚
HUANG Cui-mei(Guangzhou First People's Hospital,Guangzhou 510000,China)
出处
《中国实用医药》
2020年第29期134-136,共3页
China Practical Medicine
关键词
癫痫
中风
神经功能缺损
丙戊酸钠
Epilepsy
Stroke
Neurological deficit
Sodium valproate
