摘要
目的探讨儿童手足口病后甲脱落与病毒类型及患者体内血微量元素水平的相关性。方法117例儿童手足口病后甲脱落患者均为本院皮肤科门诊病人,肠道病毒检测情况采取回顾性分析法并同时对其行血微量元素检测。结果117例儿童手足口病后甲脱落患者病毒检测结果显示,肠道病毒感染阳性例数为91例,总阳性率为77.78%。其中肠道病毒71型(EV71)阳性例数为2例,占构成比的2.20%;柯萨奇病毒A16型(CoxA16)阳性例数为3例,占构成比的3.30%,其他EV阳性例数为86例,占构成比的94.51%。117例儿童手足口病后脱甲患者血微量元素检测结果显示,脱甲病患者体内锌、钙、镁、铁、铜水平与同期健康儿童比较,差异无统计学意义。结论引起儿童手足口病后脱甲发生的主要病原为除EV71及CoxA16以外的其他肠道病毒。脱甲的发生与病毒感染类型有关,与患者体内血微量元素水平无关。
Objective To investigate the correlation between onychomadesis related with hand foot and mouth disease(HFMD)of children and virus type and serum trace element.Methods One hundred and seventeen cases of onychomadesis related with HFMD were all outpatients of dermatology department of our hospital.A retrospective survey was conducted among viral types.The serum trace elements were detected simultaneously.Results The positive number of enterovirus infection were 91 among the 117 onychomadesis related with HFMD cases,account for 77.78%.In 91 positive cases,the positive constituent ratio were:EV positive only 2.20%(2/91),CoxA16 positive only 3.30%(3/91)and other EV positive 94.51%(86/91).The levels of zinc,calcium,magnesium,iron and copper in the onychomadesis related with HFMD had no statistical significance compared with those in healthy children.Conclusion The onychomadesis related with HFMD in children was related to the other enteroviruses,but not EV71 and CoxA16.The result demonstrated a correlation of viral types and it was not associated with serum trace element.
作者
付金玲
余勋
FU Jinling;YU Xun(Department of Dermatology,Dongguan Maternal and Child Health Care Hospital,Dongguan 523000,China;Department of Laboratory,Dongguan Maternal and Child Health Hospital,Dongguan 523000,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2020年第10期1152-1154,共3页
The Chinese Journal of Dermatovenereology
关键词
手足口病
甲脱落
肠道病毒
微量元素
Hand foot and mouth disease
Onychoptosis
Enterovirus
Trace elements
