摘要
目的了解不同妊娠期妇女全血微量元素的水平,为妊娠期微量元素的摄入与补充提供依据。方法采用安捷伦7900电感耦合等离子体质谱仪分别测定孕早、中、晚期妇女及健康非妊娠妇女全血铜、锌、钙、镁、铁5种元素水平。结果妊娠各组铁水平均低于对照组,且孕晚期组最低,差异有统计学意义(P<0.05);孕中、晚期组铁水平较孕早期组和对照组更低,差异有统计学意义(P<0.05)。妊娠各组钙、铜水平均高于对照组,差异有统计学意义(P<0.05);孕中、晚期组铜水平高于孕早期组,差异有统计学意义(P<0.05)。孕晚期组钙水平高于孕早期组,差异有统计学意义(P<0.05)。孕晚期组中,≥25~<35岁年龄段妇女铜水平较≤25岁妇女明显升高,差异有统计学意义(P<0.05)。妊娠各组铁水平异常率较对照组明显增大,差异有统计学意义(P<0.05);孕中、晚期组铁水平异常率较孕早期组增加,差异有统计学意义(P<0.05)。孕中期组锌水平异常率较孕早期组和对照组明显增加,差异均有统计学意义(P<0.05)。结论微量元素在妊娠和胎儿发育中起着重要的作用,应注重妊娠期妇女微量元素的监测与各类食物的摄入,特别是容易缺乏的铁与锌元素。
Objective To understand the levels of trace elements in the whole blood of pregnant women during different gestation periods,and to provide evidence for the intake and supplement of trace elements in gestation period.Methods The levels of copper,zinc,calcium,magnesium and iron in whole blood of women with early,middle and late pregnancy and healthy non-pregnancy were determined by Agilent 7900 Inductively Coupled Plasma Mass Spectrometry.Results The iron levels in each group of pregnancy were lower than that in the control group,and the lowest in the third trimester group,and the differences were statistically significant(P<0.05).Iron levels in the second and third trimester groups were lower than those in the first trimester group and the control group,and the differences were statistically significant(P<0.05).The levels of calcium and copper in each group of pregnancy were higher than those in the control group,and the differences were statistically significant(P<0.05).The copper levels in the second and third trimester groups were higher than that in the first trimester group,and the differences were statistically significant(P<0.05).The calcium level in the third trimester group was higher than that in the first trimester group,and the difference was statistically significant(P<0.05).In the third trimester group,the copper level of women aged more than or equal to 25 years old was significantly higher than that of women aged less than or equal to 25 years old,and the difference was statistically significant(P<0.05).The abnormal rates of iron level in each group of pregnancy was significantly higher than that in the control group,and the differences were statistically significant(P<0.05).The abnormal rates of iron level in the second and third trimester groups were higher than that in the first trimester group,and the differences were statistically significant(P<0.05).The abnormal rate of zinc level in the second trimester group was significantly higher than those in the first trimester group and the control group,and the difference was statistically significant(P<0.05).Conclusion Trace elements play an important role in the pregnancy and fetal development.Attention should be paid to the monitoring of trace elements in pregnant women and the intake of all kinds of food,especially the iron and zinc elements that are easy to be lacked.
作者
王文强
黄来荣
陈潇灵
王娅
余高旺
徐立顺
WANG Wenqiang;HUANG Lairong;CHEN Xiaoling;WANG Ya;YU Gaowang;XU Lishun(Fuzhou KingMed for Clinical Laboratory Co.,Ltd.,Fuzhou,Fujian 350003,China)
出处
《检验医学与临床》
CAS
2020年第17期2500-2503,共4页
Laboratory Medicine and Clinic
关键词
妊娠期
微量元素
电感耦合等离子体质谱
gestation period
trace elements
Inductively Coupled Plasma Mass Spectrometry
