新生儿高胆红素血症光疗不良反应研究进展被引量：35

Research progress on adverse reactions of phototherapy for neonatal hyperbilirubinemia

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摘要光疗作为一种有效的新生儿高胆红素血症的治疗手段,在临床得到广泛应用。最近研究显示,新生儿期光疗可通过氧化应激、DNA损伤等机制增加极低出生体质量儿病死率,并与儿童期肿瘤、黑色素痣、过敏性疾病及癫痫等有相关联系。因此需要进一步探索和优化光疗光源设备、改变光疗方式等,减少光疗的不良反应。文章就新生儿高胆红素血症光疗的不良反应研究进展进行综述。 As an effective treatment of neonatal hyperbilirubinemia,phototherapy has been widely applied in clinic.Recent studies have shown that neonatal phototherapy can increase the mortality of extremely low birth weight infants through such mechanisms as oxidative stress and DNA damage,and is related to childhood tumors,melanoma,allergic diseases and epilepsy.Therefore,it is necessary to further explore and optimize the light source devices and change the phototherapy approaches,etc.,to reduce the adverse reactions of phototherapy.This article reviews the research progress of the adverse reactions of neonatal hyperbilirubinemia phototherapy.

作者冯霄(综述) 童笑梅(审校) FENG Xiao;TONG Xiaomei(Peking University International Hospital,Beijing 102206,China;Peking University Third Hospital,Beijing 100191,China)

机构地区北京大学国际医院儿科北京大学第三人民医院

出处《临床儿科杂志》 CAS CSCD 北大核心 2020年第9期711-715,共5页 Journal of Clinical Pediatrics

关键词高胆红素血症光疗不良反应新生儿 hyperbilirubinemia phototherapy side effect neonate

分类号 R722.1 [医药卫生—儿科]

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