摘要
自噬是进化过程中一种高度保守的催化作用,该过程可以清除受损的细胞器以及大分子物质,同时还能清除外来的病原体,具有重要的防御功能。自噬体在60年代首次被发现,经过近些年来的研究自噬的作用以及分子机制逐渐被人们所了解,越来越多的研究发现自噬功能的异常会导致许多疾病的发生。人们发现,许多妊娠疾病的发生与自噬功能的异常有关,文章将重点叙述自噬与妊娠相关的疾病。
Autophagy is a highly conserved catalysis in the process of evolution. It can remove damaged organelles and macromolecular substances,and at the same time remove foreign pathogens and has important defense functions. Autophagosomes were first discovered in the 1960s. After the studies in recent years,the function and molecular mechanisms of autophagy gradually came to be known by people. And more and more studies have found that abnormalities in autophagy can lead to many diseases. This article will focus on the diseases which relates autophagy to pregnancy.
作者
冯晓玲
郗红燕
张杨
FENG Xiaoling;XI Hongyan;ZHANG Yang(The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,Helongjang,China;Heilongjiang University of Chinese Medicine,Harbin 150040,Helongiang,China)
出处
《辽宁中医药大学学报》
CAS
2020年第6期1-4,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(81973894)。
关键词
自噬
妊娠
先兆子痫
胎儿生长受限
早产
autophagy
pregnancy
preeclampsia
fetal growth restriction
premature birth
