摘要
目的探讨小针刀松解术联合常规西药对类风湿关节炎临床症状及类风湿因子(RF)水平的影响。方法将40例类风湿关节炎患者以数字表法随机分为对照组和观察组,各20例。对照组采用常规西药治疗,观察组在对照组基础上联合小针刀松解术治疗。比较两组临床疗效。结果观察组治疗总有效率显著高于对照组(P<0.05)。治疗后,观察组关节肿胀指数、关节压痛指数明显小于对照组,晨僵时间明显短于对照组(P<0.05)。治疗后,观察组RF、MDA水平低于对照组,SOD水平高于对照组(P<0.05)。结论小针刀松解术联合常规西药治疗类风湿关节炎能够有效提高临床效果,促进患者症状的改善,抑制炎性反应和氧自由基代谢,减少RF的表达,值得推广。
Objective To investigate the effects of small needle knife lysis combined with conventional western medicine on clinical symptoms and rheumatoid factor(RF)level of rheumatoid arthritis.Methods Forty patients with rheumatoid arthritis were randomly divided into control group and observation group by digital table method,with 20 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with small needle knife lysis on the basis of the control group.The clinical effects of the two groups were compared.Results The total effective rate of treatment of the observation group was significantly higher than that of the control group(P<0.05).After treatment,the joint swelling index and joint tenderness index of the observation group were significantly less than those of the control group,and the morning stiffness time was significantly shorter than that of the control group(P<0.05).After treatment,the levels of RF and MDA in the observation group were lower than those in the control group,while the level of SOD in the observation group was higher than that in the control group(P<0.05).Conclusion Small needle knife lysis combined with conventional western medicine in the treatment of rheumatoid arthritis can effectively improve the clinical effect,promote the improvement of patients’symptoms,inhibit inflammatory reaction and oxygen free radical metabolism,and reduce the expression of RF,which is worthy of promotion.
作者
田晶
浦元
TIAN Jing;PU Yuan(Shaanxi Sengong Hospital,Xi'an 710300,China)
出处
《临床医学研究与实践》
2020年第22期53-55,共3页
Clinical Research and Practice
关键词
小针刀松解术
西药
类风湿关节炎
临床症状
类风湿因子
small needle knife lysis
western medicine
rheumatoid arthritis
clinical symptoms
rheumatoid factor
