摘要
目的:系统评价针刺联合生物反馈治疗功能性便秘的疗效。方法:计算机检索中国知网(CNKI)、万方数据库、维普数据库(VIP)、中国生物医学文献数据库(CBM)、Pubmed、Web of science、Embase、Cochrane library,收集2019年12月25日以前关于针刺联合生物反馈治疗功能性便秘的临床随机对照试验文献,按照拟定的纳入排除标准筛选。运用RevMan 5.3软件进行Meta分析。结果:共纳入19篇文献,患者1479例。Meta分析结果显示:针刺联合生物反馈治疗功能性便秘有效率优于常规生物反馈[RR=1.24,95%CI(1.18,1.30),Z=8.62,P<0.00001],在降低直肠初始感觉阈值上与常规生物反馈相比更为明显[MD=-11.34,95%CI(-15.16,-7.53),Z=5.83,P<0.00001],差异具有统计学意义。结论:针刺联合生物反馈治疗功能性便秘较常规生物反馈疗效更好,但在改善肛管静息压、肛管收缩压、直肠最大耐受阈值方面尚缺乏有力证据,因此还需要更多高质量随机对照试验支持。
Objective:To systematic review of the efficacy of Acupuncture combined with biofeedback in the Treatment of Functional Constipation(FC).Methods:The literatures on clinical randomized controlled trials of acupuncture combined with biofeedback for FC in CNKI,Wanfang database,VIP database,CBM,Pubmed,Web of science,Embase and Cochrane library were searched by computer.The retrieval time was before December 25,2019.The original literature was screened according to the proposed inclusion and exclusion criteria,and data were analyzed by RevMan 5.3.Results:A total of 19 articles and 1479 patients were included in the study.The Meta analysis results indicated that the experimental group showed better efficacy than the control group in terms of efficiency rate[RR=1.24,95%CI(1.18,1.30),Z=7.62,P<0.00001]and the lowest threshold of rectum[MD=-11.34,95%CI(-15.16,-7.53),Z=5.83,P<0.00001].The results were statistically significant.Conclusion:Acupuncture combined with biofeedback is an effective treatment for functional constipation,which is superior to biofeedback.However,the evidences to decrease the anal resting pressure,anal systolic pressure and the maximum tolerance of the rectum are still not certain.More high-quality randomized controlled trials are needed in the future.
作者
唐立垚
贺娅楠
桑伟钰
王奇钰
高峰
Tang Liyao;He Ya’nan;Sang Wei;Wang Qiyu;Gao Feng(Gansu University of Tradional Chinese Medicine;940 Hospital,Joint Logistics Support Force of the Peopled Liberation Army of China,Lanzhou 730000,China)
出处
《亚太传统医药》
2020年第7期158-164,共7页
Asia-Pacific Traditional Medicine
基金
甘肃省自然科学基金(17JR5RA311)
全军后勤保健专项研究项目(16BJZ48)。