摘要
外周动脉疾病( PAD)最常见的病因为动脉粥样硬化,终末期患者出现肢体缺血乃至组织坏死,常因截肢而致残。外科及血管腔内治疗等方式开通血管、改善局部组织血供,可以缓解患者的临床症状,改善生活质量。但是依然有部分患者的血管解剖条件较差不适合手术,即使是血管腔内手术后有短期立竿见影的疗效,但远期有高达30%~50%的血管再狭窄率,严重影响患者的预后甚至截肢。因此,早期诊断、早期治疗是达到理想治愈的最佳手段。近年来,关于 PAD早期诊断、早期治疗的研究取得了显著的进步,相信随着这些研究的不断深入,一定能大大降低 PAD发病率,提高 PAD的治愈率,减轻家庭及社会的经济负担。
Atherosclerosis is the most common pathogenic factor resulting in peripheral arterial disease(PAD),and end-stage patients suffer from limb ischemia,tissue necrosis,and even amputation.The open surgery and endovascular treatment,which rebuild blood vessels and improve local tissue blood supply,can alleviate patients’clinical symptoms and improve their quality of life.However,there are still some patients with poor vascular anatomical conditions that are not suitable for endovascular treatment.Even if the short-term effect is immediate after endovascular surgery,the long-term rate of vascular restenosis is as high as 30%-50%,which seriously affects the prognosis of patients and even results in amputation.Therefore,early diagnosis and treatment are the best means to achieve the ideal cure.In recent years,significant progress has been made in the research on early diagnosis and treatment of PAD.It is believed that with the deepening of these studies,the incidence of PAD will be greatly reduced,the cure rate of PAD will be improved,and the economic burden on families and society will be reduced.
作者
王深明
王折存
Wang Shenming;Wang Zhecun(Department of Vascular Surgery,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China)
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2020年第5期795-799,共5页
Chinese Journal of Experimental Surgery
关键词
外周动脉疾病
下肢动脉粥样硬化闭塞
血管体检
早期治疗
Peripheral arterial disease
Arteriosclerosis obliterans
Vascular checkup
Early treatment
