摘要
目的探讨双源CT多参数成像对肺癌化疗疗效的评估价值。方法回顾性分析周口市中医院2017年5月至2018年6月通过化学治疗的肺癌患者60例,所有患者化疗前后行双源CT扫描,依据CT评价标准,分为有效组和无效组,比较两组肿瘤CT形态学变化、动静脉期标准化碘与碘覆盖值、病灶动脉强化分数。结果有效组治疗后120kv、100kv、80kv、60kv、40kv能量下CT值低于无效组(P<0.05);有效组治疗后病灶最长径较治疗前减小,无效组治疗后病灶最长径较治疗前增大,两组病灶最长径变化率比较(P<0.05);有效组与无效组治疗后平均CT值均较治疗前减少,且有效组变化率大于无效组(P<0.05);有效组动脉期标准化碘与碘覆盖值低于无效组(P<0.05);有效组治疗后病灶动脉强化分数低于无效组(P<0.05)。结论双源CT多参数成像可显示病灶形态分析强化特征,评估血管化程度,可作为肺癌化疗疗效评价的有效手段。
Objective To explore the evaluation value of dual-source CT multi-parameter imaging in curative effect of lung cancer chemotherapy.Methods A retrospective analysis was performed on 60 patients with lung cancer who underwent chemotherapy in the hospital from May 2017 to June 2018.Before and after chemotherapy,all underwent dual-source CT scans.Based on the assessment criteria of CT,they were divided into effectivetreatment group and ineffective treatment group.The morphological changes of tumor CT,standardized iodine and iodine coverage values during arteriovenous period,arterial enhancement scoreof the lesions in the two groups were compared.Results After treatment,CT values under 120kv,100kv,80kv,60kv and 40kv energy were lower in effective treatment group than ineffective treatment group (P<0.05).After treatment,lesion longest diameter in effective treatment group was reduced,while it was increased in ineffective treatment group.There were significant differences in change rate of lesion longest diameter between the two groups (P<0.05).After treatment,average CT valuesin both groups were decreased.The change rate was greater in effective treatment group than ineffective treatment group(P<0.05).The standardized iodine and iodine coverage values during arterial periodwere lowerin effective treatment group than ineffective treatment group (P<0.05).After treatment,arterial enhancement score of the lesionswas lower in effective treatment group than ineffective treatment group(P<0.05).Conclusion Dual-source CT multi-parameter imaging can display morphological features of lesions,quantificationally analyze lesion enhancement features,assessdegree of lesionvascularization,which can be applied as a useful method for evaluating curative effect of lung cancer chemotherapy.
作者
朱金奇
朱炎
孟捷
ZHU Jin-qi;ZHU Yan;MENG Jie(Department of CT Room,Zhoukou Hospital of Traditional Chinese Medicine,Zhoukou,466000,Henan Province,China)
出处
《中国CT和MRI杂志》
2020年第9期79-81,89,共4页
Chinese Journal of CT and MRI
关键词
双源CT
肺癌
化疗
疗效评价
Dual-source CT
Lung Cancer
Chemotherapy
Curative Effectevaluation
