摘要
目的:本临床试验主要是为了对比不同宫颈锥切方法治疗宫颈上皮内瘤Ⅲ级的效果。方法:本次临床试验是将2017年6月30日-2019年6月30日在笔者所在医院妇科就诊的120例宫颈上皮内瘤Ⅲ级患者作为研究对象,采用随机数字分配法将120例患者分为试验组(n=60)和对照组(n=60),试验组应用宫颈冷刀锥切术治疗,对照组应用宫颈环形电切术进行治疗;分别观察两组手术期间各项指标、术后并发症发生率及HPV持续感染率等情况。结果:试验组术中出血量为(32.57±12.67)ml,手术时间为(18.25±9.25)min,均低于对照组的(44.12±11.68)ml、(25.26±10.27)min,试验组术后1、3、6个月的HPV持续感染情况(0、1、4例)少于对照组(3、7、11例);且试验组HPV持续感染率为8.33%,显著低于对照组的35.00%,试验组并发症的发生率为13.33%,显著低于对照组的43.33%,差异有统计学意义(P<0.05)。结论:宫颈冷刀锥切除术能在一定程度上缩短手术时间,减少手术期间的出血量,特别是还能有效减少术后并发症的发生率,对患者术后的恢复有较好的疗效,可作为一种有效的手术方式供临床医生选择,值得广泛推广。
Objective:To compare the different methods of cervical conization in the treatment of cervical intraepithelial neoplasiaⅢ.Method:In this clinical trial,120 patients with cervical intraepithelial neoplasia gradeⅢwho were treated in the Department of Gynecology of our hospital from June 30,2017 to June 30,2019 were selected as the research objects,and 120 patients were randomly divided into the experimental group(n=60)and the control group(n=60).The experimental group was treated with cervical cold scalpel conization,and the control group was treated with cervical circular electrotomy.The indexes during the operation,the incidence of postoperative complications and the rate of persistent infection of HPV in the two groups were observed respectively.Result:The amount of intraoperative bleeding in the experimental group was(32.57±12.67)ml,and the operation time was(18.25±9.25)min,which were lower than(44.12±11.68)ml,(25.26±10.27)min in the control group.The persistent infection of HPV in the experimental group was 0,1 and 4 cases respectively at 1,3 and 6 months after the operation which were lower than 3,7 and 11 cases in the control group.The HPV persistent infection rate in the experimental group was 8.33%,significantly lower than 35.00%in the control group.The incidence rate of complications in the experimental group was 13.33%,which was significantly lower than 43.33%in the control group,the differences were statistically significant(P<0.05).Conclusion:The cervical cold scalpel conization can shorten the operation time and reduce the amount of bleeding during the operation to a certain extent,especially can effectively reduce the incidence of postoperative complications,and has a good effect on the recovery of patients after the operation.It can be used as an effective operation for clinicians to choose,and it is worth popularizing in clinical.
作者
胡妮
HU Ni(Ezhou Maternal and Child Health Hospital,Ezhou 436000,China)
出处
《中外医学研究》
2020年第20期145-147,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
宫颈上皮内瘤Ⅲ级
宫颈冷刀锥切除术
宫颈环形电切术
Cervical intraepithelial tumor gradeⅢ
Cervical cold scalpel conization
Cervical circular electrotomy
