摘要
[目的]评价正念干预措施(MBIs)对乳腺癌病人焦虑、抑郁症状的影响。[方法]计算机检索Web of Science、PubMed、the Cochrane Library、中国期刊全文数据库、万方数据知识服务平台和维普全文数据库中涉及正念干预措施对乳腺癌病人焦虑、抑郁症状影响的随机对照试验,检索时间为建库至2019年6月15日。2名研究员完成文献筛选、数据提取和质量评价后,使用RevMan 5.3软件进行分析。[结果]共纳入10篇文献。Meta分析结果显示:干预后正念干预组焦虑评分[SMD=-0.45,95%CI(-0.68,-0.22),P=0.0001]和抑郁评分[SMD=-0.38,95%CI(-0.60,-0.17),P=0.0004]均低于对照组,差异有统计学意义。[结论]现有证据表明:正念干预措施能有效缓解焦虑、抑郁情绪,但由于纳入研究较少且研究间异质性较高,正念干预对不同种族研究对象抑郁情绪缓解的效果还需进行多人群、大样本的研究,对于正念干预改善抑郁情绪的长期效果(>12周)仍需开展更多高质量、多中心的研究。
Objective:To evaluate effects of mindfulness-based interventions on anxiety and depression symptoms of patients with breast cancer.Methods:Randomized controlled trials on effects of anxiety and depression symptoms for patients with breast cancer,were retrieved from Web of Science,Pub Med,the Cochrane Library,CNKI,Wanfang Data and VIP.Retrieval time was from database establishment to June 15,2019.Literatures screening,data extraction and quality evaluation were carried out by two researchers.And Rev Man 5.3 software was used for taking an analysis.Results:A total of 10 randomized controlled trials were included.Meta-analysis showed that after intervention,anxiety score[SMD=-0.45,95%CI(-0.68,-0.22),P=0.0001]and depression score[SMD=-0.38,95%CI(-0.60,-0.17),P=0.0004]in mindfulness-based interventions group were lower than those of control group.And differences were statistically significant.Conclusions:Current evidence shows that mindfulness-based interventions can effectively relieve anxiety and depression.But due to small number of included studies and high heterogeneity among the studies,effect of mindfulness-based interventions on relief of anxiety and depression in research subjects with different races needs to be verified by multi-racial and large-scale researches.In addition,more high-quality,multi-center researches on long-term(>12 weeks)effects of mindfulness-based interventions on improving depression still need to be carried out.
作者
张岚
杜娟
邹振亚
纪荣建
许翠萍
ZHANG Lan;DU Juan;ZOU Zhenya;JI Rongjian;XU Cuiping(School of Nursing,Shandong University,Shandong 250012 China)
出处
《护理研究》
北大核心
2020年第14期2437-2444,共8页
Chinese Nursing Research
基金
山东省重点研发计划基金资助项目,编号:2017GSF18140。
关键词
正念干预
乳腺癌
焦虑
抑郁
META分析
mindfulness-based interventions
breast cancer
anxiety
depression
Meta-analysis
