摘要
目的探讨新疆地区糖尿病周围神经病痛性症状的危险因素,并比较汉族、维吾尔族、哈萨克族其发病率。方法收集2019年3月至2019年7月就诊于新疆医科大学第一附属医院内分泌科、疼痛科的汉族、维吾尔族、哈萨克族糖尿病患者,从中筛选出符合纳入标准的患者,共240例,将其分为无痛性糖尿病周围神经病变组(painless-DPN组)及有痛性糖尿病周围神经病变组(painful-DPN组),对患者入院时的身高、体重、体重指数(BMI)、腰围等一般情况,以及个人史和血糖、血脂化验结果进行调查,完成调查问卷表。结果三个民族就诊患者DPN的痛性症状发病率具有明显差异性(P均<0.05),维吾尔族的发病率(42%)高于汉族(28.4%)和哈萨克族(16.7%);中学/中专组[OR(95%CI)=2.894(1.450~5.777)],小学及以下组[OR(95%CI)=2.865(1.087~7.550)];血糖定期监测组[OR(95%CI)=1.733(0.746~4.027)],偶尔监测组[OR(95%CI)=3.663(1.727~7.768)],不监测组[OR(95%CI)=5.011(0.842~29.832)];患病年限[OR(95%CI)=1.082(1.030~1.137)]和空腹血糖[OR(95%CI)=1.146(1.043~1.259)]为各民族人群痛性糖尿病周围神经病变发生的危险因素。结论新疆地区各民族的糖尿病周围神经病变患者应加强对自身健康的管理,增强对DPN的了解与对自身血糖水平的管控意识,减少痛性症状的发生。
Objective To investigate the related risk factors of patients with diabetic peripheral neuropathy(DPN)in Xinjiang area and comparison of the incidence in Han,Uygur and Kazakh populations.Methods Two hundred and forty patients with diabetes of Han,Uygurs,Kazakh population admitted to the Department of Endocrinology and Pain Medicine in First Affiliated Hospital of Xinjiang Medical University from March 2019 to July 2019,were collected,who met with the criteria of diabetic peripheral neuropathy.According to the clinical symptoms,the patients were divided into painless diabetic peripheral neuropathy group(painless-DPN group)and painful diabetic peripheral neuropathy group(painful-DPN group).The patients'height,weight,BMI and other general conditions,as well as their personal history,blood glucose and blood lipid were investigated,and the questionnaire was completed during the admission.Results The incidences of painful symptoms in DPN was significantly different among the three ethnic groups(all P<0.05).The incidences of DPN in Uygur population(42%)is higher than that in Han(28.4%)and Kazakh(16.7%).Middle schools/secondary school[OR(95%CI)=2.894(1.450-5.777)],primary school and below[OR(95%CI)=2.865(1.087-7.550)];regular blood glucose monitoring[OR(95%CI)=1.733(0.746-4.027)],occasional monitoring[OR(95%CI)=3.663(1.727-7.768)],no monitor[OR(95%CI)=5.011(0.842-29.832)];the duration of sick[OR(95%CI)=1.082(1.030-1.137)]and fasting blood-glucose[OR(95%CI)=1.146(1.043-1.259)]were the risk factors for painful diabetic peripheral neuropathy.Conclusion The management of their health,enhancing the understanding of DPN,awareness of blood glucose control,and reducing the incidences of painful symptoms should be strengthened in the population of Xinjiang area.
作者
雷舒煜
吴蓍妍
刘磊
席鹏
李亦梅
Lei Shuyu;Wu Shiyan;Liu Lei;Xi Peng;Li Yimei(Department of Pain Medicine,the First Affiliated of Xinjiang Medical University,Urumqi City,Xinjiang 830054,China)
出处
《中华疼痛学杂志》
2020年第2期123-129,共7页
Chinese Journal Of Painology
关键词
周围神经病变
糖尿病
危险因素
汉族
维吾尔族
哈萨克族
Peripheral neuropathy
Diabetes mellitus
Risk factor
Hah nationality
Uygur nationality
Kazakh nationality
