摘要
在无金属条件下通过自由基偶联反应,实现了醚类与N-氧化物的C-2烷基化反应,反应条件温和,只需加入氧化剂二叔丁基过氧化物(DTBP)就能够以中等至高产率获得各种所需产物.
The C-2 alkylation of ethers and N-oxides was achieved via free radical coupling reaction under metal-free conditions.The reaction conditions are mild,and the desired products can be obtained in medium to high yields with the addition of the oxidant di-tert-butyl peroxide(DTBP).
作者
董道青
李光辉
陈德茂
孙媛媛
韩晴晴
王祖利
徐鑫明
于贤勇
Dong Daoqing;Li Guanghui;Chen Demao;Sun Yuanyuana;Han Qingqing;Wang Zuli;Xu Xinming;Yu Xianyong(College of Chemistry and Pharmaceutical Sciences,Qingdao Agricultural University,Qingdao,Shandong 266109;College of Chemistry and Chemical Engineering,Yantai University,Yantai,Shandong 264005;School of Chemistry and Chemical Engineering,Hunan University of Science and Technology,Xiangtan,Hunan 411201)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2020年第6期1766-1771,共6页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.21772107)
山东省重点研发计划(No.2019GSF108017)资助项目。
