摘要
制备了一种以三苯胺、辛基芴和丙二腈分别作为给体、π桥和受体基团的扭转型D-π-A结构的用于检测Fe^3+离子的纳米颗粒(TA-DF-BDM/PSMA NPs)荧光探针. TA-DF-BDM/PSMA NPs具有610 nm红光发射,并具有大的斯托克斯位移(203nm左右).TA-DF-BDM/PSMANPs可在纯水中检测Fe^3+,并具有较高的选择性和灵敏度以及低的检出限(0.9883μmol/L).更重要的是TA-DF-BDM/PSMA NPs具有稳定的光物理性质,并且具有可逆性、较好的生物相容性和较低的细胞毒性,使其可应用于生物成像研究.
In this work,the novel fluorescent probes for detecting Fe^3+ions based on nanoparticles(TA-DF-BDM/PSMA NPs)of fluorescence material with twisting D-π-A configuration was designed and prepared,in which triphenylamine(TA),9,9-dioctylfluorene(DF)and benzylidenemalononitrile(BDM)serve as electron donor(D)unit,πconjugated unit,and electron acceptor(A)unit,respectively.TA-DF-BDM/PSMA NPs exhibit red-emission peak located at 610 nm in photoluminescence spectrum and larger stokes shifts(ca.203 nm).And,TA-DF-BDM/PSMA NPs exhibit high selectivity for detecting Fe^3+ions in pure water with high sensitivity and low detection limit of 0.9833μmol/L.More importantly,TA-DFBDM/PSMA NPs show such properties as good photophysical stability,reversibility,excellent biocompatibility and low cytotoxicity,which can be utilized in bioimaging investigations.
作者
刘幸
陶鹏
杨晶晶
刘雯
王华
王学宁
赵强
黄维扬
许并社
Liu Xing;Tao Peng;Yang Jingjing;Liu Wen;Wang Hua;Wang Xuening;Zhao Qiang;Wong Wai-yeung;Xu Bingshe(Key Laboratory of Interface Science and Engineering in Advanced Materials of Ministry of Education,Taiyuan University of Technology,Taiyuan,Shanxi 030024;Department of Applied Biology and Chemical Technology,The Hong Kong Polytechnic University,Hong Kong 999077;Department of Cardiovascular Surgery,Shanxi Baiqiuen Hospital(Shanxi Academy of Medical Sciences),Taiyuan,Shanxi 030032;Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials,Nanjing University of Posts and Telecommunications(NUPT),Nanjing 210023)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2020年第6期1588-1597,共10页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(Nos.61775155,61605138,61705156,61905120)
山西省科技创新重点团队(No.201601D021043)
香港理工大学(Nos.1-ZE1C,847S)资助项目.
