摘要
为了评价10%盐酸沃尼妙林预混剂对鸡的安全性,将雌雄各半的64只广东黄麻鸡随机分为4组,每组分别按体重以空白、1次单剂量(10 mg/kg)、1次3倍(30 mg/kg)和1次5倍(50 mg/kg)单剂量的10%盐酸沃尼妙林预混剂混饲给药,观察各组鸡临床表现、体重变化和饲料消耗,并于给药前1 d、给药结束后第7、14 d剖检鸡进行病理学检查、血液生理生化检测。结果显示:各组生长性能指标、血液生理指标及血清生化指标均差异不显著(P>0.05),病理学检查结果无明显病理变化。提示:10%盐酸沃尼妙林预混剂对鸡安全。
In order to evaluate the safety of valnemulin hydrochloride premix for chickens,64 Guangdong yellow chickens(half males and half females)of 1-month old were selected and randomly divided into four diet groups:zero,single,triple and quintuple dosages(10 mg/kG)of 10%valnemulin hydrochloride premix.Their clinical manifestations,weight changes and fodder consumption were observed.Autopsies were conducted on the chickens 1 day before drug administration,and 7 days and 14 days after dosing for pathological examination and blood physiological and biochemical tests,respectively.We found that there was no difference in growth performance among these different groups(P>0.05)and no dose-dependent change was found in the physiological and biochemical indexes of their blood(P>0.05).These results indicated that 10%valnemulin hydrochloride premix is safe when applied to chickens.
作者
钟佳莲
林祚贵
阮国荣
ZHONG Jialian;LIN Zuogui;RUAN Guorong(College of Animal Science,Fujian Vocational College of Agriculture,Fuzhou 350119,China)
出处
《畜牧与兽医》
北大核心
2020年第6期57-60,共4页
Animal Husbandry & Veterinary Medicine
基金
福建省现代农业产业技术体系专项资金(2017CYTX0625)
2017年福建农业职业技术学院院级科研项目(2017JS008)资助。
关键词
盐酸沃尼妙林
黄麻鸡
安全性
Valnemulin hydrochloride
Guangdong yellow chicken
safety
