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“调营充络”论治法对椎基底动脉迂曲并后循环缺血性眩晕的临床研究 被引量:10

Clinical Effect of "Nourishing and Regulating Collaterals" Therapy on Vertebrobasilar Artery Tortuosity Complicated with PCIV
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摘要 目的探讨"调营充络"论治法对椎基底动脉迂曲并后循环缺血性眩晕(Posterior circulation ischemic vertigo,PCIV)患者的临床治疗效果。方法选择2015年1月—2018年5月在医院及协作医院神经内科门诊治疗或住院治疗的椎基底动脉迂曲合并PCIV的患者80例,按照随机数字的方法分为对照组和治疗组各40例,对照组单纯给予西药治疗,治疗组在对照组基础上,以中医"调营充络"论治法为指导给予中药口服。对比两组治疗前后的眩晕障碍量表(DHI)评分。对比两组的眩晕治疗效果。对比两组治疗前后的经颅多普勒(TCD)结果。对比两组治疗前后的脑干诱发电位(BAEP)结果。对比两组治疗结束后半年内的眩晕再发作次数。结果经过治疗后两组的DHI评分均降低,治疗组的降低幅度大于对照组(t=2.682,P<0.05),治疗组的眩晕治疗效果优于对照组(z=-2.422,P<0.05),经过治疗后,两组患者经颅多普勒(TCD)结果正常的比例均提升,治疗组的升高幅度大于对照组(χ~2=5.000,P<0.05),经过治疗后,两组患者脑干诱发电位(BAEP)结果正常的比例均提升,治疗组的升高幅度大于对照组(χ~2=4.680,P<0.05)。结论使用"调营充络"论治法治疗椎基底动脉迂曲并PCIV的患者,可以提升治疗效果,为该种疾病的治疗开辟新的思路,值得推荐。 Objective To explore the therapeutic effect of"nourishing and regulating collaterals"on patients with vertebrobasilar artery tortuosity and PCIV.Methods Eighty patients with vertebrobasilar artery tortuosity complicated with PCIV were selected from January 2015 to May 2018.The patients were divided into control group(n=40)and treatment group(n=40).The control group was treated with western medicine alone,while the treatment group was given oral Chinese medicine under the guidance of the traditional Chinese medicine"regulating Ying and replenishing collaterals"method on the basis of the control group.The scores of vertigo disorder scale(DHI)before and after treatment were compared between the two groups.The therapeutic effect of vertigo was compared between the two groups.The results of transcranial Doppler(TCD)before and after treatment were compared between the two groups.The results of brainstem evoked potential(BAEP)before and after treatment were compared between the two groups.We compared the recurrence times of vertigo within half a year after the end of treatment between the two groups.Results After treatment,the DHI scores of the two groups decreased,and the decrease range of the treatment group was greater than that of the control group(t=2.682,P<0.05).The vertigo treatment effect of the treatment group was better than that of the control group(z=-2.422,P<0.05).After treatment,the proportion of normal TCD results in both groups increased,and the increase in the treatment group was greater than that in the control group(χ~2=5.000,P<0.05).After treatment,the proportion of normal results of brain stem evoked potential(BAEP)in both groups increased,and the increase in treatment group was greater than that in control group(χ~2=4.680,P<0.05).Conclusion The treatment of vertebrobasilar artery tortuosity and PCIV with the method of"nourishing and regulating collaterals"can improve the therapeutic effect and open up new ideas for the treatment of this disease,which is worthy of recommendation.
作者 张志军 王宝亮 张士金 张爱玲 ZHANG Zhijun;WANG Baoliang;ZHANG Shijin;ZHANG Ailing(Traditional Chinese Medicine Department,Zhengzhou Peoples Hospital,Zhengzhou 45000,Henan,China;Encephalopathy Department,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,Henan,China;Department of Neurology,Zhengzhou Peoples Hospital,Zhengzhou 450000,Henan,China)
出处 《中华中医药学刊》 CAS 北大核心 2020年第5期56-59,共4页 Chinese Archives of Traditional Chinese Medicine
基金 国家中医药管理局第六批全国老中医药专家学术经验继承工作室项目(国中医药办人教发[2017]125,国中医药人教教育便函[2019]42,豫中医科教[2019]5) 河南省中医药科学研究专项(2018ZY3018)。
关键词 椎基底动脉迂曲 后循环缺血性眩晕 脑血管变异 vertebrobasilar artery tortuosity posterior circulation ischemic vertigo cerebrovascular variation
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