摘要
目的分析加味补中益气汤辅助治疗慢性阻塞性肺疾病伴呼吸衰竭的效果。方法选择2018年2月~2019年2月于河北省沧州市献县中医医院进行治疗的慢性阻塞性肺疾病伴呼吸衰竭患者92例为研究样本,采取随机数字表法分成常规组和实验组,每组46例。常规组予以西医基础治疗,实验组予以西医基础治疗及加味补中益气汤治疗,疗程4周。比较两组治疗前后中医证候积分、心率、呼吸、氧分压及二氧化碳分压、肺活量、第1秒用力呼气量及呼气峰流速、St.George′s呼吸疾病调查问卷得分,并观察两组治疗效果。结果治疗后,两组中医证候积分均较治疗前降低(P <0.05),且实验组低于常规组(P <0.05)。治疗后,两组心率、呼吸频率均较治疗前变慢,二氧化碳分压水平较治疗前降低,氧分压水平较治疗前升高(P <0.05),且实验组改善情况优于常规组(P <0.05)。治疗后,两组肺活量、第1秒用力呼气量及呼气峰流速均较治疗前升高(P <0.05),且实验组高于常规组(P <0.05)。实验组总有效率高于常规组(P <0.05)。治疗后,两组疾病表现、疾病影响及活动障碍得分均较治疗前降低(P <0.05),且实验组低于常规组(P <0.05)。结论加味补中益气汤辅助治疗慢性阻塞性肺疾病伴呼吸衰竭可提升患者疗效,改善其临床表现和肺功能,进而提高生活质量,具有一定的临床应用价值。
Objective To analyze clinical effect of Jiawei Buzhong Yiqi Decoction in the auxiliary treatment of chronic obstructive pulmonary disease with respiratory failure.Methods Ninety-two patients of chronic obstructive pulmonary disease with respiratory failure treated in Xianxian Hospital of Traditional Chinese Medicine of Cangzhou City in Hebei Province from February 2018 to February 2019 were selected as study samples.They were divided into routine group and experimental group by random number table method,with 46 cases in each group.Routine group was treated with basic Western medicine,experimental group was treated with basic Western medicine and Jiawei Buzhong Yiqi Decoction for 4 weeks.Traditional Chinese medicine syndrome score,heart rate,respiration rate,oxygen partial pressure,carbon dioxide partial pressure,vital capacity,forced expiratory volume in the first second and peak expiratory velocity,St.George′s respiratory disease questionnaire score between two groups were compared before and after treatment.The therapeutic effect of two groups was observed.Results After treatment,the scores of traditional Chinese medicine syndromes in two groups were lower than those before treatment(P<0.05),and the scores in experimental group were lower than those in routine group(P<0.05).After treatment,the heart rate and respiration of two groups were slower than those before treatment,the level of carbon dioxide partial pressure was lower than that before treatment,the level of oxygen partial pressure was higher than that before treatment(P<0.05),and the improvement of experimental group was better than that of routine group(P<0.05).After treatment,the vital capacity,forced expiratory volume in the first second and peak expiratory velocity in two groups were higher than those before treatment(P<0.05),and experimental group was higher than that in routine group(P<0.05).Total effective rate of experimental group was higher than that of routine group(P<0.05).After treatment,the scores of disease performance,disease influence and activity disorderin two groups were lower than those before treatment(P<0.05),and the scores in experimental group were lower than those in routine group(P<0.05).Conclusion The auxiliary treatment of Jiawei Buzhong Yiqi Decoction can improve the curative effect,clinical performance,lung function and life quality of patients with chronic obstructive pulmonary disease and respiratory failure.It has certain clinical application value.
作者
安会明
苗丹丹
吕蓓蓓
祁树彬
AN Huiming;MIAO Dandan;LYU Beibei;QI Shubin(Intensive Care Unit,Xianxian Hospital of Traditional Chinese Medicine of Cangzhou City in Hebei Province,Hebei Province,Xianxian 062250,China)
出处
《中国医药导报》
CAS
2020年第17期153-157,共5页
China Medical Herald
基金
河北省中医药管理局科研计划项目(2019282)。
关键词
呼吸衰竭
慢性阻塞性肺疾病
辅助
加味补中益气汤
证候积分
肺功能
Respiratory failure
Chronic obstructive pulmonary disease
Auxiliary
Jiawei Buzhong Yiqi Decoction
Symptom score
Pulmonary function
