摘要
目的探讨IgM抗体实验室检测结果对流行性出血热患者诊治和防治的意义。方法选取我院2017年7月~2019年6月出血热患者180例,对血清标本进行流行性出血热IgM抗体酶联免疫吸附试验(ELISA),并对此试验的特异性、灵敏度、阴阳性预测值及有效率分析。结果流行性出血热抗体阳性患者56例,阳性率31.11%。此次研究ELISA试验检测流行性出血热IGM抗体的特异性、灵敏度、诊断有效率分别是99.17%、91.67%和96.67%。结论酶联免疫吸附试验(ELISA)检测流行性出血热IgM抗体,实验简单快速,灵敏度高,特异性较强,可为临床早期流行性出血热的诊断提供依据。
Objective To investigate the significance of laboratory test results of IgM antibodies in the diagnosis,treatment and prevention of patients with epidemic hemorrhagic fever.Methods 180 patients with hemorrhagic fever in our hospital from July 2017 to June 2019 were selected.Serum specimens were given enzyme-linked immunosorbent assay(ELISA)for IgM antibody against epidemic hemorrhagic fever,and the specificity,sensitivity,negative and positive predictive value,and effectiveness of this test were analyzed.Results There were 56 patients with positive antibody of epidemic hemorrhagic fever,with a positive rate of 31.11%.The specificity,sensitivity,and diagnostic effectiveness of the ELISA test for detecting IGM antibodies against epidemic hemorrhagic fever in this study were 99.17%,91.67%,and 96.67%,respectively.Conclusion Enzyme-linked immunosorbent assay(ELISA)used to detect the IgM antibody against epidemic hemorrhagic fever is simple and rapid,with high sensitivity and strong specificity.It can provide a basis for the clinical diagnosis of early epidemic hemorrhagic fever.
作者
赵禹
ZHAO Yu(Clinical Laboratory of Microbiology,Benxi Disease Prevention and Control Center in Liaoning Province,Benxi 117000,China)
出处
《中国现代医生》
2020年第12期147-149,共3页
China Modern Doctor
关键词
流行性出血热
IGM抗体
酶联免疫吸附试验
肾综合征出血热
Epidemic hemorrhagic fever
IgM antibody
Enzyme-linked immunosorbent assay(ELISA)
Hemorrhagic fever with renal syndrome
