摘要
立体定向放射治疗(stereotactic body radiation therapy,SBRT)是一种高精度的放射治疗技术,可以通过较少分次的照射提供高剂量、高精度的放射治疗。SBRT能够显著改善肝细胞癌(hepatocellular carcinoma,HCC)患者的局部控制和生存,对于等待肝移植的患者来说,SBRT也可以是一种有效和安全的桥接治疗。此外,SBRT已经显示出联合免疫检查点抑制剂应用的潜在作用。本文将就SBRT治疗HCC的有效性和安全性,并对SBRT联合免疫治疗进行综述。
Stereotactic body radiation therapy(SBRT)is a high-precision radiotherapy technology that provides high-dose and highprecision radiotherapy through less fractional irradiation.SBRT can significantly improve local control and survival rates in patients with hepatocellular carcinoma(HCC).SBRT can also be an effective and safe bridging therapy for patients awaiting liver transplantation.Moreover,recent studies have reported the potential effects of the combination of SBRT and immune checkpoint inhibitors.This article reviews the safety and efficacy of SBRT in the treatment of HCC,in anticipation of the future application of SBRT in combination with immunotherapy.
作者
宋勇春(综述)
袁智勇(审校)
Yongchun Song;Zhiyong Yuan(Department of Radiation Oncology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin Key laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,Tianjin 300060,China)
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2020年第8期427-430,共4页
Chinese Journal of Clinical Oncology
关键词
肝细胞癌
放射治疗
立体定向放射治疗
免疫治疗
hepatocellular carcinoma
radiotherapy
stereotactic body radiation therapy
immunotherapy
