摘要
目的:分析尿路感染病原菌分布及其耐药性,为临床治疗尿路感染提供依据。方法:收集弋矶山医院2016年1月~2019年6月住院患者尿培养阳性菌株资料,分析其细菌学结果。结果:共检出745株菌株,其中革兰阴性菌648株(87.0%),以大肠埃希菌、肺炎克雷伯菌和鲍曼不动杆菌为主;革兰阳性菌97株(13.0%),以粪肠球菌和金黄色葡萄球菌为主。大肠埃希菌、肺炎克雷伯菌中产超广谱β-内酰胺酶菌(ESBLs)菌检出率分别为65.6%、7.9%;鲍曼不动杆菌检出率为1.9%,对亚胺培南耐药率为92.9%。粪肠球菌检出率为6.8%,检出1株耐万古霉素粪肠球菌;耐甲氧西林金黄色葡萄球菌(MRSA)检出率为4.0%。结论:弋矶山医院尿路感染细菌以产ESBLs大肠埃希菌为主,加β内酰胺酶抑制剂抗菌药物是治疗产ESBLs大肠埃希菌有效药物。
Objective:To analyze the distribution and resistance of bacteria in urinary tract infection for clinical evidences in the treatment of such infection.Methods:The data were collected from inpatients with positive strains of bacteria confirmed by laboratory urine study in Yijishan Hospital of Wannan Medical College between January 2016 and June 2019,and the pathogens were analyzed.Results:A total of 745 strains of bacteria were isolated,in which 648 were Gram-negative bacteria(87.0%)consisting of Escherichia coli,Klebsiella pneumoniae and Acinetobacter baumannii,and 97 were Gram-positive(13.0%)primarily comprising Enterococcus faecalis and Staphylococcus aureus.Detected extended-spectrumβ-lactamase(ESBL)-producing Escherichia coli and Klebsiella pneumoniae were respectively 65.6%and 7.9%.The detected rate of Acinetobacter baumannii was 1.9%,and the resistance rate was over 92.9%for imipenem.6.8%Enterococcus faecalis was detected,in which 1 strain was found resistant to vancomycin.The detected rate of Methicillin-resistant Staphylococcus aureus(MRSA)was 4.0%.Conclusion:The bacteria causing urinary tract infection were dominated by ESBL-producing Escherichia coli in our inpatients,and antimicrobial drug plus beta lactamase inhibitor should be effective in the treatment of such infection.
作者
杨沿浪
杨晓明
林鑫
王淼
YANG Yanlang;YANG Xiaoming;LIN Xin;WANG Miao(Department of Nephrology,The first Affiliated Hospital of Wanan Medical College,Wuhu 241001,China)
出处
《皖南医学院学报》
CAS
2020年第2期137-139,共3页
Journal of Wannan Medical College
基金
安徽省卫生和计划生育委员会科研计划项目(2016QK071)。
关键词
尿路感染
细菌
耐药
urinary tract infection
bacteria
drug resistance
