摘要
抑郁症确切的病理生理学机制尚不清楚,近红外光谱脑功能成像技术是近年来新兴的一种基于血流动力学原理的非侵入式功能神经影像学技术,广泛应用于精神科,具有辅助诊断抑郁症的临床价值。此外,近红外光谱成像可以与其他神经调控物理治疗结合以检测大脑皮层的血流动力学及氧合状态变化,有望为相关技术参数设定及疗效预后提供有利指导。
The pathophysiological mechanism of depressive disorder is still unclear.Functional nearinfrared spectroscopy(fNIRS)is a useful neuroimaging technique based on hemodynamic principles for the non-invasive investigation of brain in motion.It is widely used in psychiatry and considered to be a potential auxiliary diagnostic method based on the current evidence.In addition,fNIRS can be combined with other neuromodulation therapies to detect changes in hemodynamics and oxygenation status of the cerebral cortex,providing valuable advices for setting related technical parameters and prognosis.
作者
张福旭
张天宏
刘晓华
Zhang Fuxu;Zhang Tianhong;Liu Xiaohua(Department of Psychiatry,Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China)
出处
《神经疾病与精神卫生》
2020年第2期116-120,共5页
Journal of Neuroscience and Mental Health
关键词
抑郁症
功能近红外光谱成像
认知任务
神经调控治疗
综述
Depressive disorder
Functional near-infrared spectroscopy
Cognitive task
Neuromodulation therapy
Review
