摘要
以去氢弯孢霉素核磁共振波谱(NMR)解析为例,讲授本科化学和药学相关专业波谱分析课程NMR解析。去氢弯孢霉素结构包含苯环、双键、酚羟基、羰基和酯基等常见基团,NMR信号几乎无重叠、辨识度高,非常适合作为核磁共振波谱结构解析中化学位移、耦合常数和二维核磁共振波谱的授课内容。
This paper illustrates the teaching of the undergraduate curriculum "spectral analysis" by the NMR analysis of dehydrocurvularin. Dehydrocurvularin possesses several functional groups including benzene ring, double bond, phenolic hydroxyl, carbonyl, and ester group, and showed distinct and recognizable NMR signals, which is suitable for teaching of chemical shifts, coupling constants, and 2 D NMR analysis.
作者
董建伟
李雪娇
蔡乐
缪应纯
Jianwei Dong;Xuejiao Li;Le Cai;Yingchun Miao(College of Chemistry and Environmental Science,Qujing Normal University,Qujing 655011,Yunnan Province,P.R.China;School of Chemical Science and Technology,Yunnan University,Kunming 650091,P.R.China)
出处
《大学化学》
CAS
2020年第3期113-119,共7页
University Chemistry
基金
云南省研究生优质课程项目
曲靖师范学院教育教学改革研究项目(JGXM201809)。
关键词
波谱分析
核磁共振波谱
结构解析
去氢弯孢霉素
Spectral analysis
Nuclear magnetic resonance spectrum
Structure elucidation
Dehydrocurvularin
