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现代服药辟谷改善心血管疾病危险因素的回顾性临床观察 被引量:14

Retrospective clinical study of modern Chinese medication fasting ameliorating cardiovascular disease risk factors
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摘要 目的:探讨现代服药辟谷治疗前后患者心血管疾病危险因素变化情况。方法:采用回顾性、自身对照的临床研究方法,共纳入192例,分别于辟谷前、辟谷后观察患者心血管疾病危险因素变化情况。结果:患者体重、血压、血糖、胰岛素抵抗指数(HOMA-IR)、甘油三酯、胰岛素样生长因子-1(IGF-1)等辟谷前后差异有统计学意义(P<0.01)。辟谷前心血管疾病危险因素已超过临床危险临界值的患者变化程度较正常受试者差异有统计学意义(P<0.01)。结论:现代服药辟谷对超重/肥胖、高血压、高血糖、高甘油三酯等心血管疾病危险因素有改善作用,可降低IGF-1,并可良性双向调节血压。 Objective:To analyze the changes in patients’cardiovascular disease risk factors before and after modern Chinese medication fasting.Methods:A self-controlled retrospective clinical study was conducted,and 192 patients were enrolled to observe the changes in cardiovascular disease risk factors before and after the treatment.Results:After the treatment,compared with baseline values,patients’body weight,blood pressure,blood glucose,HOMA-IR,triglyceride,and IGF-1 decreased significantly(P<0.01).Patients with baseline values exceeded the clinical risk threshold before the treatment benefited more than normal subjects(P<0.01).Conclusion:Modern Chinese medication fasting has good effects on cardiovascular disease risk factors including overweight/obesity,hypertension,hyperglycemia,and hypertriglyceridemia can significantly reduce IGF-1 and regulate blood pressure bidirectionally.
作者 张汀滢 李辉 张丽 柯斌 孙佳盼 刘桃丽 黄颖娟 陈贤华 刘孟婷 罗导航 秦鉴 ZHANG Ting-ying;LI Hui;ZHANG Li;KE Bin;SUN Jia-pan;LIU Tao-li;HUANG Ying-juan;CHEN Xian-hua;LIU Meng-ting;LUO Dao-hang;QIN Jian(The Seventh Affiliated Hospital,Sun Yat-Sen University,Shenzhen 518107,China;The First Affiliated Hospital,SUN Yat-sen University,Guangzhou 510080,China)
出处 《中华中医药杂志》 CAS CSCD 北大核心 2020年第3期1613-1616,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 国家自然科学基金面上项目(No.81874498) 深圳市卫生系统临床研究项目(No.SZLY2018002)。
关键词 现代服药辟谷 热量限制 心血管疾病 危险因素 Modern Chinese medication fasting Calorie restriction Cardiovascular disease Risk factors
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