摘要
传统中医早有"胃不和则卧不安"的临床观察经验,而现代医学关于"菌群-肠-脑轴"学说认为,肠道内环境的微生物菌群的稳态与神经内分泌网络失调机制疾病密切相关。本研究提示,肠道菌群失调导致的胃肠脾运化功能失常可能是失眠的重要机制,通过调节肠道菌群-肠-脑轴的平衡,成为失眠临床治疗的新思路。
Traditional Chinese medicine has long had the clinical observation experience of"stomach discord means reclining restlessness",while the modern medical theory of"microbiota-gut-brain axis"believes that the homeostasis of microbiota in the intestinal environment is closely related to the disorders of neuroendocrine network mechanism.It is suggested that gastrointestinal and splenic dysfunctions caused by intestinal flora disorders may be an important mechanism for insomnia,and by regulating the balance of intestinal flora-intestinal-cerebral axis,it will be a new idea for clinical treatment of insomnia.
作者
李雅方
梁瑞琼
邱鸿钟
Li Yafang;Liang Ruiqiong;Qiu Hongzhong(School of economics and management,Guangzhou University of Chinese medicine,Guangzhou 510006,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2020年第7期2494-2498,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家中医药管理局委托专项课题(GZY-FJS-2019-010):中医药科研“西化”问题及其对策研究,负责人:邱鸿钟
关键词
肠道菌群
菌-肠-脑轴
失眠
Intestinal flora
Bacteria-enterobrain-axis
Insomnia
