摘要
目的应用超声剪切波弹性成像技术定量测定乳腺实性肿块的弹性模量值,探究乳腺肿块良恶性病变的弹性硬度的差异及规律。方法选取2017年3月至2018年12月上海市浦东新区公利医院超声科就诊检查的女性乳腺肿瘤病人51例54个病灶,测量乳腺肿块的弹性模量值,比较乳腺良恶性病灶的各弹性参数的差异。结果54个乳腺病灶中,恶性病灶23个,良性病灶31个。乳腺良性病灶与恶性病灶的SWE指标即最大值(Emax)[(34.9±9.9)比(72.1±23.7)kPa]、平均值(Emean)[(25.7±8.0)比(47.8±11.3)kPa]、最小值(Emin)[(16.4±5.2)比(28.7±9.1)kPa]、标准差(Esd)[(5.7±2.0)比(17.3±10.0)kPa]、病变/脂肪弹性比(Eratio)[(4.5±2.8)比(10.7±3.3)kPa]比较,均差异有统计学意义(P<0.05)。把SWE指标值绘制ROC曲线,Emax、Emean、Emin、Esd、Eratio的ROC曲线下面积(AUC)分别为0.955、0.931、0.879、0.926和0.898,Emax的AUC高于Emean、Emin、Eratio。结论超声剪切波弹性成像技术对乳腺肿块良恶性的鉴别诊断有较好的应用价值。
Objective To determine the elastic modulus of breast solid mass quantitatively by shear wave elastography and explore the differences and regularity of elastic hardness of benign and malignant breast lesions.Methods From March 2017 to December 2018,54 lesions of 51 female breast cancer patients diagnosed by surgery or biopsy,were selected from the ultrasound department of Shanghai Pudong New Area Gongli hospital.The elastic modulus of the breast mass was measured and the differences in elastic pa rameters of benign and malignant breast lesions were compared.Results Among the 54 breast lesions,23 were malignant lesions and 31 were benign lesions.The SWE index between the benign and malignant breasts,maximum value(Emax)[(34.9±9.9)vs.(72.1±23.7)kPa],mean value(Emean)[(25.7±8.0)vs.(47.8±11.3)kPa],minimum value(Emin)[(16.4±5.2)vs.(28.7±9.1)kPa],standard deviation(Esd)[(5.7±2.0)vs.(17.3±10.0)kPa],lesion/fat elasticity ratio(Eratio)[(4.5±2.8)vs.(10.7±3.3)kPa]were statistically sig nificant(P<0.05).The SWE index values were plotted as ROC curves.The AUC of Emax,Emean,Emin,Esd,Eratio were 0.955,0.931,0.879,0.926 and 0.898,in which the AUC of Emax was higher than that of Emean,Emin,and Eratio.Conclusion The new re al time shear wave elastography has a good application value in the differential diagnosis of benign and malignant breast tumors.
作者
万永林
傅晓红
刘秋云
陈鸣
恽蓓
伍健
高琳珺
沈燕
吴墅
刘淼
WAN Yonglin;FU Xiaohong;LIU Qiuyun;CHEN Ming;YUN Bei;WU Jian;GAO Linjun;SHEN Yan;WU Shu;LIU Miao(Department of Ultrasound,Gongli Hospital,Pudong New Area,Shanghai,200135,China;Department of General Surgery,Gongli Hospital,Pudong New Area,Shanghai,200135,China;Department of Pathology,Gongli Hospital,Pudong New Area,Shanghai,200135,China)
出处
《安徽医药》
CAS
2020年第5期912-914,共3页
Anhui Medical and Pharmaceutical Journal
基金
上海市浦东新区公利医院青年基金资助计划(2016YQNJJ 12)。
关键词
乳腺疾病
超声检查
乳房
弹性成像技术
诊断
Breast diseases
Ultrasonography
mammary
Elasticity imaging techniques
Diagnosis
