摘要
目的探讨脑梗死合并糖尿病患者颅内外动脉粥样硬化性狭窄的特征。方法选取2017年3月至2019年4月西北工业大学医院收治的68例脑梗死合并糖尿病患者设为观察组;并选取同期收治的68例单纯脑梗死患者设为对照组。所有患者入院后均给予DSA检查,根据DSA检查结果比较患者颅内、外分段的粥样硬化性狭窄分布情况。结果两组患者的出血性梗塞发生率比较,差异无统计学意义(P>0.05);观察组患者的腔隙性梗塞发生率显著低于对照组,差异具有统计学意义(P<0.05);观察组患者的大片梗塞、多灶性梗塞及再发性梗塞发生率均显著高于对照组,差异具有统计学意义(P<0.05)。脑梗死合并糖尿病患者的狭窄部位分别为颈内动脉颅外段、颈内动脉颅内段、大脑前动脉、大脑中动脉、大脑后动脉、椎动脉颅外段、椎动脉颅内段。其中大脑前动脉与颈内动脉颅外段狭窄情况发生率最高,椎动脉颅外段与椎动脉颅内段狭窄情况发生率最低。结论脑梗死合并糖尿病患者颅内动脉粥样硬化性狭窄较为明显,临床应加强患者的血糖水平控制,制定有效的干预措施。
Objective To investigate the characteristics of intracranial and extracranial atherosclerotic stenosis in patients with cerebral infarction and diabetes mellitus.Methods From March 2017 to April 2019,68 patients with cerebral infarction and diabetes mellitus admitted in Hospital of northwestem polytechnical university were selected as observation group,and 68 patients with simple cerebral infarction in the same period were selected as control group.All patients were given DSA examination after admission,and the distribution of atherosclerotic stenosis in the intracranial and extracranial segments was compared according to the results of DSA examination.Results There was no significant difference in the incidences of hemorrhagic infarction between the two groups(P>0.05);the incidence of lacunar infarction in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05);the incidences of massive infarction,multifocal infarction and recurrent infarction in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).The stenosis sites of patients with cerebral infarction and diabetes mellitus were extracranial segment of internal carotid artery,intracranial segment of internal carotid artery,anterior cerebral artery,middle cerebral artery,posterior cerebral artery,extracranial segment of vertebral artery and intracranial segment of vertebral artery.Among them,the incidences of stenosis in the anterior cerebral artery and extracranial segment of internal carotid artery were highest,and those in the extracranial segment of vertebral artery and intracranial segment of vertebral artery were lowest.Conclusion Intracranial atherosclerotic stenosis is more obvious in patients with cerebral infarction and diabetes mellitus.It is necessary to strengthen the control of blood glucose levels and formulate effective measures for intervention.
作者
牛爽
康蓓
郭荷娜
NIU Shuang;KANG Bei;GUO He-na(Hospital of Northwestem Polytechnical University,Xi'an 710000;Shaanxi Provincial People's Hospital,Xi'an 710065,China)
出处
《临床医学研究与实践》
2020年第8期130-131,134,共3页
Clinical Research and Practice
关键词
脑梗死
糖尿病
颅内外动脉粥样硬化性狭窄
腔隙性梗塞
cerebral infarction and diabetes mellitus
intracranial and extracranial atherosclerotic stenosis
lacunar infarction
