摘要
为探索发芽粟米对高血脂症小鼠血脂调节和抗氧化作用。用高脂乳剂灌胃小鼠建立高脂模型,观察发芽粟米对小鼠体重、肝指数变化、血清和肝脏血脂及抗氧化能力的影响。与高脂模型组相比,喂养发芽粟米的高血脂症小鼠,体重和肝脏指数均呈降低趋势;血清和肝脏血脂中,发芽粟米显著降低高血脂症小鼠中总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平(P<0.05),显著升高高密度脂蛋白胆固醇(HDL-C)水平(P<0.05);血清和肝组织中,发芽粟米显著降低丙二醛(MDA)含量(P<0.05),显著升高还原型谷胱甘肽(GSH)含量(P<0.05),增强超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GSH-Px)活性(P<0.05);结果表明:发芽粟米可调节脂质代谢和提高抗氧化能力。
To study the regulation of germinated millet on blood lipid and antioxidant in hyperlipemia mice,the high fat mice was established by feeding mice with high fat emulsion.The effects of germinated millet on weight,liver index,serum lipid,liver lipid,and antioxidant capactity of mouse were observed.Compared with the high fat model group,the weight and liver index of experimental mice were decreased.Meanwhile,the levels of TC,TG,LDL-C in the serum lipid and liver lipid were significantly lower(P<0.05),and the level of HDL-C was significantly higher(P<0.05).In the serum and liver tissue,germinated milletsignificantly reduced the MDA concentration(P<0.05),increased the GSH concentration(P<0.05),and improved SOD,CAT and GSH-Px activities(P<0.05).The germinated millet could regulatethe hyperlipidemiaand improveantioxidant capacity.
作者
张佳丽
张爱霞
赵巍
李少辉
刘莹莹
刘敬科
郝庆红
陈秀勇
Zhang Jiali;Zhang Aixia;Zhao Wei;Li Shaohui;Liu Yingying;Liu Jingke;Hao Qinghong;Chen Xiuyong(Institute of Millet Crops,Hebei Academy of Agriculture and Forestry Sciences,National Foxtail Millet Improvement Center,Minor Cereal Crops Laboratory of Hebei Province,Shijiazhuang 050035;College of life Sciences Agricultural University of University of Hebei,Baoding 071001;Zunhua City Bureau of Industry and Information 3,Tangshan 064200)
出处
《中国粮油学报》
EI
CAS
CSCD
北大核心
2020年第3期37-44,共8页
Journal of the Chinese Cereals and Oils Association
基金
国家自然科学基金(31771902)
河北省科技计划项目(17227108D)
河北省农林科学院创新工程课题资助(2019-2-2-1)。
关键词
发芽粟米
高血脂症
血脂调节
抗氧化作用
germinated millet
hyperlipidemia
lipid regulation
antioxidant
